Towards the development of DCIS risk prediction models

Ductal carcinoma in situ (DCIS) has a variable natural history, with a poorly understood biology. In this issue of Cancer Cell, Strand et. al. use two well-annotated DCIS repositories to identify an 812-gene classifier that associates with high risk of DCIS recurrence and define novel DCIS subtypes...

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Veröffentlicht in:	Cancer cell 2022-12, Vol.40 (12), p.1461-1464
Hauptverfasser:	Behbod, Fariba, Khan, Seema Ahsan
Format:	Artikel
Sprache:	eng
Schlagworte:	Breast Neoplasms - genetics Carcinoma, Intraductal, Noninfiltrating - genetics Carcinoma, Intraductal, Noninfiltrating - pathology Female Humans
Online-Zugang:	Volltext
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Beschreibung
Zusammenfassung:	Ductal carcinoma in situ (DCIS) has a variable natural history, with a poorly understood biology. In this issue of Cancer Cell, Strand et. al. use two well-annotated DCIS repositories to identify an 812-gene classifier that associates with high risk of DCIS recurrence and define novel DCIS subtypes that informs future studies. Ductal carcinoma in situ (DCIS) has a variable natural history, with a poorly understood biology. In this issue of Cancer Cell, Strand et. al. use two well-annotated DCIS repositories to identify an 812-gene classifier that associates with high risk of DCIS recurrence and define novel DCIS subtypes that informs future studies.
ISSN:	1535-6108 1878-3686
DOI:	10.1016/j.ccell.2022.11.010