The impact of youth‐onset type 2 diabetes on postoperative wound healing complications

Youth‐onset type 2 diabetes mellitus is associated with a more rapid decline in β cells, and earlier onset of medical complications compared to adult‐onset diabetes. However, its impact on surgical wounds remains less clear. Therefore, this study aimed to determine whether youth‐onset diabetes is a...

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Veröffentlicht in:Wound repair and regeneration 2023-03, Vol.31 (2), p.187-192
Hauptverfasser: Brydges, Hilliard T., McDonnell, Grace, Nasr, Hani Y., Chaya, Bachar F., Onuh, Ogechukwu C., Alfonso, Allyson R., Ceradini, Daniel J.
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Sprache:eng
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Zusammenfassung:Youth‐onset type 2 diabetes mellitus is associated with a more rapid decline in β cells, and earlier onset of medical complications compared to adult‐onset diabetes. However, its impact on surgical wounds remains less clear. Therefore, this study aimed to determine whether youth‐onset diabetes is a risk factor for wound healing complications in the 30‐day postoperative period. To do so, the National Surgical Quality Improvement Program Database years 2012–2019 was analysed. Patients aged 18–24 with non‐insulin‐dependent diabetes were included. Outcomes assessed included wound infections, wound dehiscence, readmissions, and reoperation. Univariate analysis identified differences between the diabetic and non‐diabetic cohorts after which, multivariate logistic regression was employed to control for potential confounding. Analysis included 1589 diabetic and 196,902 non‐diabetic patients ages 18–24. The diabetic cohort exhibited a higher proportion of female (83.8% vs. 55.2%, p 
ISSN:1067-1927
1524-475X
DOI:10.1111/wrr.13064