The Effectiveness and Safety of the Duodenal-Jejunal Bypass Liner (DJBL) for the Management of Obesity and Glycaemic Control: a Systematic Review and Meta-Analysis of Randomized Controlled Trials

Introduction The duodenal-jejunal bypass liner (DJBL) is a less-invasive treatment of obesity and type 2 diabetes mellitus (T2DM). Methods This is a systematic review and meta-analysis including randomized clinical trials (RCTs) comparing DJBL versus sham or pharmacotherapies aiming to evaluate the...

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Veröffentlicht in:	Obesity surgery 2023-02, Vol.33 (2), p.585-599
Hauptverfasser:	Yvamoto, Erika Yuki, de Moura, Diogo Turiani Hourneaux, Proença, Igor Mendonça, do Monte Junior, Epifanio Silvino, Ribeiro, Igor Braga, Ribas, Pedro Henrique Boraschi Vieira, Hemerly, Matheus Cândido, de Oliveira, Victor Lira, Sánchez-Luna, Sergio A., Bernardo, Wanderley Marques, de Moura, Eduardo Guimarães Hourneaux
Format:	Artikel
Sprache:	eng
Schlagworte:	Bariatric Surgery - adverse effects Diabetes Mellitus, Type 2 - etiology Duodenum - surgery Humans Jejunum - surgery Medicine Medicine & Public Health Meta-analysis Obesity - etiology Obesity - surgery Obesity, Morbid - surgery Randomized Controlled Trials as Topic Review Surgery Systematic review Treatment Outcome
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Zusammenfassung:	Introduction The duodenal-jejunal bypass liner (DJBL) is a less-invasive treatment of obesity and type 2 diabetes mellitus (T2DM). Methods This is a systematic review and meta-analysis including randomized clinical trials (RCTs) comparing DJBL versus sham or pharmacotherapies aiming to evaluate the effectiveness and safety of DJBL. Results Ten RCTs (681 patients) were included. The DJBL group showed superior excess weight loss (+ 11.4% [+ 7.75 to + 15.03%], p
ISSN:	0960-8923 1708-0428
DOI:	10.1007/s11695-022-06379-0