Neutralization capacity of recombinant antivenoms based on monoclonal antibodies and nanobodies

Neutralization capacity of recombinant antivenoms based on monoclonal antibodies and nanobodies

•Neutralization capacities are provided for recombinant snakebite antivenoms.•Neutralization capacities are compared between conventional and recombinant antivenoms.•Recombinant antivenoms may have higher neutralization capacities than conventional antivenoms.

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Veröffentlicht in:Toxicon (Oxford) 2023-01, Vol.222, p.106991-106991, Article 106991
Hauptverfasser: Ljungars, Anne, Laustsen, Andreas H.
Format: Artikel
Sprache:eng
Schlagworte:
Antibodies, Monoclonal
Antivenins
Dosing
Envenoming therapy
Humans
Monoclonal antibodies
Recombinant antivenom
Single-Domain Antibodies
Snake Bites
Snakebite envenoming
Toxin neutralization
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container_title Toxicon (Oxford)
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creator Ljungars, Anne
Laustsen, Andreas H.
description •Neutralization capacities are provided for recombinant snakebite antivenoms.•Neutralization capacities are compared between conventional and recombinant antivenoms.•Recombinant antivenoms may have higher neutralization capacities than conventional antivenoms.
doi_str_mv 10.1016/j.toxicon.2022.106991
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subjects Antibodies, Monoclonal
Antivenins
Dosing
Envenoming therapy
Humans
Monoclonal antibodies
Recombinant antivenom
Single-Domain Antibodies
Snake Bites
Snakebite envenoming
Toxin neutralization
title Neutralization capacity of recombinant antivenoms based on monoclonal antibodies and nanobodies
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