Neutralization capacity of recombinant antivenoms based on monoclonal antibodies and nanobodies

Neutralization capacity of recombinant antivenoms based on monoclonal antibodies and nanobodies

•Neutralization capacities are provided for recombinant snakebite antivenoms.•Neutralization capacities are compared between conventional and recombinant antivenoms.•Recombinant antivenoms may have higher neutralization capacities than conventional antivenoms.

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Bibliographische Detailangaben
Veröffentlicht in:Toxicon (Oxford) 2023-01, Vol.222, p.106991-106991, Article 106991
Hauptverfasser: Ljungars, Anne, Laustsen, Andreas H.
Format: Artikel
Sprache:eng
Schlagworte:
Antibodies, Monoclonal
Antivenins
Dosing
Envenoming therapy
Humans
Monoclonal antibodies
Recombinant antivenom
Single-Domain Antibodies
Snake Bites
Snakebite envenoming
Toxin neutralization
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Beschreibung
Zusammenfassung:•Neutralization capacities are provided for recombinant snakebite antivenoms.•Neutralization capacities are compared between conventional and recombinant antivenoms.•Recombinant antivenoms may have higher neutralization capacities than conventional antivenoms.
ISSN:0041-0101
1879-3150
DOI:10.1016/j.toxicon.2022.106991