A glimpse into TriC’s magic chamber of secrets

Chaperones are important for protein folding, but visualizing this process has proven to be exceptionally difficult. In this issue of Cell, Frydman and colleagues have succeeded in watching tubulin being folded by its chaperonin TRiC at near-atomic resolution. Chaperones are important for protein fo...

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Veröffentlicht in:Cell 2022-12, Vol.185 (25), p.4679-4681
1. Verfasser: Bardwell, James C.A.
Format: Artikel
Sprache:eng
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Zusammenfassung:Chaperones are important for protein folding, but visualizing this process has proven to be exceptionally difficult. In this issue of Cell, Frydman and colleagues have succeeded in watching tubulin being folded by its chaperonin TRiC at near-atomic resolution. Chaperones are important for protein folding, but visualizing this process has proven to be exceptionally difficult. In this issue of Cell, Frydman and colleagues have succeeded in watching tubulin being folded by its chaperonin TRiC at near-atomic resolution.
ISSN:0092-8674
1097-4172
DOI:10.1016/j.cell.2022.11.007