Age and the cascade impact on coronary flow reserve (CFR) and discordance of fractional flow reserve and non‐hyperemic pressure ratios (NHPR)
Key Points CFR decreases with age because hyperemic flow is reduced. Reduced hyperemic flow affects FFR but not NHPR, contributing to a higher rate of discordance between pressure ratios in the elderly. Using a dichotomous age cut off of 60 years, the impact of age in patients with discordant physio...
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| Veröffentlicht in: | Catheterization and cardiovascular interventions 2022-12, Vol.100 (7), p.1206-1207 |
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| container_title | Catheterization and cardiovascular interventions |
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| creator | Kern, Morton J. |
| description | Key Points
CFR decreases with age because hyperemic flow is reduced.
Reduced hyperemic flow affects FFR but not NHPR, contributing to a higher rate of discordance between pressure ratios in the elderly.
Using a dichotomous age cut off of 60 years, the impact of age in patients with discordant physiologic indices is minimal. |
| doi_str_mv | 10.1002/ccd.30502 |
| format | Article |
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CFR decreases with age because hyperemic flow is reduced.
Reduced hyperemic flow affects FFR but not NHPR, contributing to a higher rate of discordance between pressure ratios in the elderly.
Using a dichotomous age cut off of 60 years, the impact of age in patients with discordant physiologic indices is minimal.</description><identifier>ISSN: 1522-1946</identifier><identifier>EISSN: 1522-726X</identifier><identifier>DOI: 10.1002/ccd.30502</identifier><identifier>PMID: 36465005</identifier><language>eng</language><publisher>United States: Wiley Subscription Services, Inc</publisher><subject>Blood Flow Velocity ; Cardiac Catheterization ; CFLO ; CORB ; Coronary Angiography ; coronary blood flow/physiology/microvascular function ; coronary flow ; Coronary Stenosis - diagnostic imaging ; Coronary Stenosis - therapy ; Coronary Vessels - diagnostic imaging ; Discordance ; FFR ; fractional flow reserve ; Fractional Flow Reserve, Myocardial ; Humans ; Predictive Value of Tests ; Severity of Illness Index ; Treatment Outcome</subject><ispartof>Catheterization and cardiovascular interventions, 2022-12, Vol.100 (7), p.1206-1207</ispartof><rights>2022 Wiley Periodicals LLC.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c2432-da56cd0279d54a614fdf524ab0643c011611d1babd100cf4e127898daee246b73</cites><orcidid>0000-0002-8425-3042</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1002%2Fccd.30502$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1002%2Fccd.30502$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,776,780,1411,27903,27904,45552,45553</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/36465005$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Kern, Morton J.</creatorcontrib><title>Age and the cascade impact on coronary flow reserve (CFR) and discordance of fractional flow reserve and non‐hyperemic pressure ratios (NHPR)</title><title>Catheterization and cardiovascular interventions</title><addtitle>Catheter Cardiovasc Interv</addtitle><description>Key Points
CFR decreases with age because hyperemic flow is reduced.
Reduced hyperemic flow affects FFR but not NHPR, contributing to a higher rate of discordance between pressure ratios in the elderly.
Using a dichotomous age cut off of 60 years, the impact of age in patients with discordant physiologic indices is minimal.</description><subject>Blood Flow Velocity</subject><subject>Cardiac Catheterization</subject><subject>CFLO</subject><subject>CORB</subject><subject>Coronary Angiography</subject><subject>coronary blood flow/physiology/microvascular function</subject><subject>coronary flow</subject><subject>Coronary Stenosis - diagnostic imaging</subject><subject>Coronary Stenosis - therapy</subject><subject>Coronary Vessels - diagnostic imaging</subject><subject>Discordance</subject><subject>FFR</subject><subject>fractional flow reserve</subject><subject>Fractional Flow Reserve, Myocardial</subject><subject>Humans</subject><subject>Predictive Value of Tests</subject><subject>Severity of Illness Index</subject><subject>Treatment Outcome</subject><issn>1522-1946</issn><issn>1522-726X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2022</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp1kc1KJDEUhYPM4P_CFxgCs-letN6kklTXUkodBRlFFNwVqeTWWFJVqUm6lN75BvqM8ySm7VZwwNW9cL9z4J5DyB6DfQbAD4yx-wlI4Gtkk0nOJylXt99WO8uE2iBbIdwDQKZ4tk42EiWUBJCb5PnwD1LdWTq7Q2p0MNoirdtemxl1HTXOu077Oa0a90g9BvQPSEf5ydX4TWXrEBGrO4PUVbTyUVdHRfNZsEA71_17ermb9-ixrQ3t4zEMHqnXURLo6Pfp5dV4h3yvdBNwdzW3yc3J8XV-Ojm_-HWWH55PDBcJn1gtlbHA08xKoRUTla0kF7oEJRIDjCnGLCt1aWNAphLIeDrNplYjcqHKNNkmo6Vv793fAcOsaOMr2DS6QzeEgqciBZjGBCP68z_03g0-_rigpJAppExGarykjHcheKyK3tdtjK5gUCxaKmJLxVtLkf2xchzKFu0H-V5LBA6WwGPd4PxrpyLPj5aWr15enA4</recordid><startdate>20221201</startdate><enddate>20221201</enddate><creator>Kern, Morton J.</creator><general>Wiley Subscription Services, Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7T5</scope><scope>7U9</scope><scope>H94</scope><scope>K9.</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0002-8425-3042</orcidid></search><sort><creationdate>20221201</creationdate><title>Age and the cascade impact on coronary flow reserve (CFR) and discordance of fractional flow reserve and non‐hyperemic pressure ratios (NHPR)</title><author>Kern, Morton J.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c2432-da56cd0279d54a614fdf524ab0643c011611d1babd100cf4e127898daee246b73</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2022</creationdate><topic>Blood Flow Velocity</topic><topic>Cardiac Catheterization</topic><topic>CFLO</topic><topic>CORB</topic><topic>Coronary Angiography</topic><topic>coronary blood flow/physiology/microvascular function</topic><topic>coronary flow</topic><topic>Coronary Stenosis - diagnostic imaging</topic><topic>Coronary Stenosis - therapy</topic><topic>Coronary Vessels - diagnostic imaging</topic><topic>Discordance</topic><topic>FFR</topic><topic>fractional flow reserve</topic><topic>Fractional Flow Reserve, Myocardial</topic><topic>Humans</topic><topic>Predictive Value of Tests</topic><topic>Severity of Illness Index</topic><topic>Treatment Outcome</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Kern, Morton J.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Immunology Abstracts</collection><collection>Virology and AIDS Abstracts</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>MEDLINE - Academic</collection><jtitle>Catheterization and cardiovascular interventions</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Kern, Morton J.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Age and the cascade impact on coronary flow reserve (CFR) and discordance of fractional flow reserve and non‐hyperemic pressure ratios (NHPR)</atitle><jtitle>Catheterization and cardiovascular interventions</jtitle><addtitle>Catheter Cardiovasc Interv</addtitle><date>2022-12-01</date><risdate>2022</risdate><volume>100</volume><issue>7</issue><spage>1206</spage><epage>1207</epage><pages>1206-1207</pages><issn>1522-1946</issn><eissn>1522-726X</eissn><abstract>Key Points
CFR decreases with age because hyperemic flow is reduced.
Reduced hyperemic flow affects FFR but not NHPR, contributing to a higher rate of discordance between pressure ratios in the elderly.
Using a dichotomous age cut off of 60 years, the impact of age in patients with discordant physiologic indices is minimal.</abstract><cop>United States</cop><pub>Wiley Subscription Services, Inc</pub><pmid>36465005</pmid><doi>10.1002/ccd.30502</doi><tpages>2</tpages><orcidid>https://orcid.org/0000-0002-8425-3042</orcidid></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1522-1946 |
| ispartof | Catheterization and cardiovascular interventions, 2022-12, Vol.100 (7), p.1206-1207 |
| issn | 1522-1946 1522-726X |
| language | eng |
| recordid | cdi_proquest_miscellaneous_2747008152 |
| source | MEDLINE; Wiley Online Library Journals Frontfile Complete |
| subjects | Blood Flow Velocity Cardiac Catheterization CFLO CORB Coronary Angiography coronary blood flow/physiology/microvascular function coronary flow Coronary Stenosis - diagnostic imaging Coronary Stenosis - therapy Coronary Vessels - diagnostic imaging Discordance FFR fractional flow reserve Fractional Flow Reserve, Myocardial Humans Predictive Value of Tests Severity of Illness Index Treatment Outcome |
| title | Age and the cascade impact on coronary flow reserve (CFR) and discordance of fractional flow reserve and non‐hyperemic pressure ratios (NHPR) |
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