Age and the cascade impact on coronary flow reserve (CFR) and discordance of fractional flow reserve and non‐hyperemic pressure ratios (NHPR)

Age and the cascade impact on coronary flow reserve (CFR) and discordance of fractional flow reserve and non‐hyperemic pressure ratios (NHPR)

Key Points CFR decreases with age because hyperemic flow is reduced. Reduced hyperemic flow affects FFR but not NHPR, contributing to a higher rate of discordance between pressure ratios in the elderly. Using a dichotomous age cut off of 60 years, the impact of age in patients with discordant physio...

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Veröffentlicht in:Catheterization and cardiovascular interventions 2022-12, Vol.100 (7), p.1206-1207
1. Verfasser: Kern, Morton J.
Format: Artikel
Sprache:eng
Schlagworte:
Blood Flow Velocity
Cardiac Catheterization
CFLO
CORB
Coronary Angiography
coronary blood flow/physiology/microvascular function
coronary flow
Coronary Stenosis - diagnostic imaging
Coronary Stenosis - therapy
Coronary Vessels - diagnostic imaging
Discordance
FFR
fractional flow reserve
Fractional Flow Reserve, Myocardial
Humans
Predictive Value of Tests
Severity of Illness Index
Treatment Outcome
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Zusammenfassung:Key Points CFR decreases with age because hyperemic flow is reduced. Reduced hyperemic flow affects FFR but not NHPR, contributing to a higher rate of discordance between pressure ratios in the elderly. Using a dichotomous age cut off of 60 years, the impact of age in patients with discordant physiologic indices is minimal.
ISSN:1522-1946
1522-726X
DOI:10.1002/ccd.30502