Corrigendum to “PFOS-induced thyroid hormone system disrupted rats display organ-specific changes in their transcriptomes” [Environ. Pollut. 305 (2022) 119340]
•PFOS exposure decrease T4, T3, rT3 and T1Ac in adult male rats.•PFOS reduces thyroid hormone concentrations without activating the HPT-axis.•PFOS alters gene expression in hypothalamus, pituitary, thyroid and liver.•PFOS dysregulates axon function and vesicle transport genes in hypothalamus.•Compro...
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Veröffentlicht in: | Environmental pollution (1987) 2023-01, Vol.317, p.120709-120709, Article 120709 |
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container_title | Environmental pollution (1987) |
container_volume | 317 |
creator | Davidsen, Nichlas Ramhøj, Louise Lykkebo, Claus Asger Kugathas, Indusha Poulsen, Rikke Rosenmai, Anna Kjerstine Evrard, Bertrand Darde, Thomas A. Axelstad, Marta Bahl, Martin Iain Hansen, Martin Chalmel, Frederic Licht, Tine Rask Svingen, Terje |
description | •PFOS exposure decrease T4, T3, rT3 and T1Ac in adult male rats.•PFOS reduces thyroid hormone concentrations without activating the HPT-axis.•PFOS alters gene expression in hypothalamus, pituitary, thyroid and liver.•PFOS dysregulates axon function and vesicle transport genes in hypothalamus.•Compromised gut microbiome had no significant effect on PFOS-induced DEGs. |
doi_str_mv | 10.1016/j.envpol.2022.120709 |
format | Article |
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subjects | Endocrine disrupting chemicals HPT-Axis Perfluoroalkyl Perfluorooctane sulfonate PFAS PFOS Thyroid Thyroid hormone Transcriptomics Vancomycin |
title | Corrigendum to “PFOS-induced thyroid hormone system disrupted rats display organ-specific changes in their transcriptomes” [Environ. Pollut. 305 (2022) 119340] |
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