Effect of amniotic membrane and platelet‐rich fibrin membrane on bone healing post endodontic surgery: An ultrasonographic, randomized controlled study

The use of membrane barriers and bone grafting materials in endodontic surgery promotes healing by regeneration rather than repair by scar tissue. Due to its valuable regenerative and therapeutic properties, the human amniotic membrane can support ideal periapical rehabilitation and promote better h...

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Veröffentlicht in:Journal of tissue engineering and regenerative medicine 2022-12, Vol.16 (12), p.1208-1222
Hauptverfasser: Johri, Saumya, Verma, Promila, Tikku, Aseem Prakash, Bains, Rhythm, Kohli, Neera
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Sprache:eng
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Zusammenfassung:The use of membrane barriers and bone grafting materials in endodontic surgery promotes healing by regeneration rather than repair by scar tissue. Due to its valuable regenerative and therapeutic properties, the human amniotic membrane can support ideal periapical rehabilitation and promote better healing after surgery. The current trial aimed to evaluate the amniotic membrane's healing potential and compare it with platelet‐rich fibrin using color doppler sonography. The current study is a randomized, double‐blinded, parallel‐group, single‐center study. Thirty‐four systematically healthy individuals requiring endodontic surgery who fulfilled all inclusion and exclusion criteria were selected and randomly placed in two groups. Surgical curettage of the bony lesion was performed and filled with hydroxyapatite graft. Amniotic membrane (Group 1) and platelet‐rich fibrin (Group 2) were placed over the bony crypt, and the flap was sutured back. The lesion's surface area and vascularity were the parameters assessed with ultrasound and color doppler. and observations: The groups found a significant difference in mean vascularity at 1 month and mean vascularity change from baseline to 1 month (p 
ISSN:1932-6254
1932-7005
DOI:10.1002/term.3362