More than growth: Phytohormone-regulated transcription factors controlling plant immunity, plant development and plant architecture

Activation of immunity by exogenous signals or mutations leading to autoimmunity has long been associated with decreased plant growth, known as the growth-defense tradeoff. Originally thought to be a redirection of metabolic resources towards defense and away from growth, recent studies have demonstrated that growth and defense can be uncoupled, indicating that metabolic regulation is not solely responsible for the growth-defense tradeoff. Immunity activation has effects on plant development beyond the reduction of plant biomass, including changes in plant architecture. Phytohormone signaling pathways, and crosstalk between these pathways, are responsible for regulating plant growth and development, and plant defense responses. Here we review the hormonal regulation of transcription factors that play roles in both defense and development, with a focus on their effects on plant architecture, and suggest the targeting of these transcription factors to increase plant immunity and change plant growth and form for enhancement of agronomical traits. •Activation of immunity changes plant growth and plant development.•These changes in development affect plant architecture and yield.•Transcription factors (TFs) mediate these developmental and immune changes.•TF expression and specificity can be engineered for plant architecture and immunity.