Smart Nano‐switch with Flexible Modulation of Ion Transport Using Multiple Environmental Stimuli

In this work, we demonstrate a unique nano‐switch with triple environmental stimuli based on the action of functional copolymer brushes in a single conical nanochannel. This nanodevice flexibly and efficiently modulates ion transport properties under the influence of three environmental stimuli: light, pH and temperature. The triple factors can not only play a regulatory role independently, but their synergistic cooperation could fully activate the ionic gate and reversibly control the gating direction. In addition, the nano‐switch can switch transport properties on demand in the face of complex combinations of different factors. This work promotes the development of intelligent bionic ion channels, which holds promise for biosensing, energy conversion and biomedical research. A biomimetic solid‐state nanochannel has been designed to respond sensitively to triple environmental stimuli (light, pH and temperature), which are functionalized by copolymer brushing. The unique synergistic modulation of triple factors allows the nanochannel to have excellent ion‐transport properties.