Comparison of aqueous humor ascorbic acid level in smokers and non-smokers

In this study, we studied effect of smoking on ascorbic acid level in aqueous humor. A cohort of 112 individuals undergoing cataract surgery for senile cataract (mean ± SD age-65 ± 8 years) was sub-grouped as smoker (n = 56) and non-smoker (n = 56) based on smoking habit. The aqueous humor sample wa...

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Veröffentlicht in:Experimental eye research 2023-01, Vol.226, p.109302-109302, Article 109302
Hauptverfasser: Garg, Anshul, Rewri, Parveen
Format: Artikel
Sprache:eng
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Zusammenfassung:In this study, we studied effect of smoking on ascorbic acid level in aqueous humor. A cohort of 112 individuals undergoing cataract surgery for senile cataract (mean ± SD age-65 ± 8 years) was sub-grouped as smoker (n = 56) and non-smoker (n = 56) based on smoking habit. The aqueous humor sample was collected in beginning of the surgery and quantitative ascorbic acid estimation was done by colorimetric method (spectrophotometry at λ = 578 nm) using commercially available assay kits using the auto-analyzer assay procedure. The mean (±SD) aqueous humor ascorbic acid level was 1396 ± 629 μmol/L among non-smokers and 774 ± 436 μmol/L among smokers (p 
ISSN:0014-4835
1096-0007
DOI:10.1016/j.exer.2022.109302