Adding data to gut feelings

Adding data to gut feelings

Pain-sensing neurons detect environmental insults and tissue injury, driving avoidance behavior and the local release of neuropeptides. Two related papers in this issue of Cell report that gut-innervating pain neurons sense bacterial presence to both shape the constituents of the gut microbiome and...

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Veröffentlicht in:Cell 2022-10, Vol.185 (22), p.4046-4048
Hauptverfasser: Marsland, Benjamin J, Harris, Nicola L
Format: Artikel
Sprache:eng
Schlagworte:
Emotions
Gastrointestinal Microbiome
Humans
Inflammation
Neuropeptides
Pain
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Beschreibung
Zusammenfassung:Pain-sensing neurons detect environmental insults and tissue injury, driving avoidance behavior and the local release of neuropeptides. Two related papers in this issue of Cell report that gut-innervating pain neurons sense bacterial presence to both shape the constituents of the gut microbiome and protect against excessive inflammation.
ISSN:0092-8674
1097-4172
DOI:10.1016/j.cell.2022.10.002