Did circular DNA shape the evolution of mammalian genomes?
Extrachromosomal circular DNA (eccDNA) can shape the genomes of somatic cells, but how it impacts genomes across generations is largely unexplored. We propose that genomes can rearrange via circular intermediates across generations and show that up to 6% of a mammalian genome can have changed gene o...
Gespeichert in:
| Veröffentlicht in: | Trends in biochemical sciences (Amsterdam. Regular ed.) 2023-04, Vol.48 (4), p.317-320 |
|---|---|
| Hauptverfasser: | , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 320 |
|---|---|
| container_issue | 4 |
| container_start_page | 317 |
| container_title | Trends in biochemical sciences (Amsterdam. Regular ed.) |
| container_volume | 48 |
| creator | Holt, Sylvester Arrey, Gerard Regenberg, Birgitte |
| description | Extrachromosomal circular DNA (eccDNA) can shape the genomes of somatic cells, but how it impacts genomes across generations is largely unexplored. We propose that genomes can rearrange via circular intermediates across generations and show that up to 6% of a mammalian genome can have changed gene order through eccDNA. |
| doi_str_mv | 10.1016/j.tibs.2022.09.010 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_2728465806</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>S0968000422002699</els_id><sourcerecordid>2728465806</sourcerecordid><originalsourceid>FETCH-LOGICAL-c351t-6c8541830d18d36b56691ceb773ebb34ead1bf8a0b7829955b8a98f76f40d0703</originalsourceid><addsrcrecordid>eNp9kDtPwzAURi0EglL4AwzII0vCtZM4DkJCVctLqmCB2bKdG-oqj2Inlfj3pCowMt3lfEe6h5ALBjEDJq7Xce9MiDlwHkMRA4MDMmGJ4FGacHFIJlAIGQFAekJOQ1gDsCzPs2NyMjIS0kJMyM3CldQ6b4dae7p4mdGw0huk_Qopbrt66F3X0q6ijW4aXTvd0g9suwbD3Rk5qnQd8PznTsn7w_3b_Clavj4-z2fLyCYZ6yNhZZYymUDJZJkIkwlRMIsmzxM0JklRl8xUUoPJJS-KLDNSF7LKRZVCCTkkU3K192589zlg6FXjgsW61i12Q1A85zIVmQQxonyPWt-F4LFSG-8a7b8UA7VrptZq10ztmiko1NhsHF3--AfTYPk3-Y00Ard7AMcvtw69CtZha7F0Hm2vys795_8GUFJ7hA</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2728465806</pqid></control><display><type>article</type><title>Did circular DNA shape the evolution of mammalian genomes?</title><source>MEDLINE</source><source>ScienceDirect Journals (5 years ago - present)</source><creator>Holt, Sylvester ; Arrey, Gerard ; Regenberg, Birgitte</creator><creatorcontrib>Holt, Sylvester ; Arrey, Gerard ; Regenberg, Birgitte</creatorcontrib><description>Extrachromosomal circular DNA (eccDNA) can shape the genomes of somatic cells, but how it impacts genomes across generations is largely unexplored. We propose that genomes can rearrange via circular intermediates across generations and show that up to 6% of a mammalian genome can have changed gene order through eccDNA.</description><identifier>ISSN: 0968-0004</identifier><identifier>EISSN: 1362-4326</identifier><identifier>DOI: 10.1016/j.tibs.2022.09.010</identifier><identifier>PMID: 36280496</identifier><language>eng</language><publisher>England: Elsevier Ltd</publisher><subject>Animals ; deletion ; DNA, Circular - genetics ; eccDNA ; evolution ; mammal ; Mammals - genetics ; meiosis ; synteny ; transposition</subject><ispartof>Trends in biochemical sciences (Amsterdam. Regular ed.), 2023-04, Vol.48 (4), p.317-320</ispartof><rights>2022 The Authors</rights><rights>Copyright © 2022 The Authors. Published by Elsevier Ltd.. All rights reserved.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c351t-6c8541830d18d36b56691ceb773ebb34ead1bf8a0b7829955b8a98f76f40d0703</cites><orcidid>0000-0003-4996-7012</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/j.tibs.2022.09.010$$EHTML$$P50$$Gelsevier$$Hfree_for_read</linktohtml><link.rule.ids>314,780,784,3550,27924,27925,45995</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/36280496$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Holt, Sylvester</creatorcontrib><creatorcontrib>Arrey, Gerard</creatorcontrib><creatorcontrib>Regenberg, Birgitte</creatorcontrib><title>Did circular DNA shape the evolution of mammalian genomes?</title><title>Trends in biochemical sciences (Amsterdam. Regular ed.)</title><addtitle>Trends Biochem Sci</addtitle><description>Extrachromosomal circular DNA (eccDNA) can shape the genomes of somatic cells, but how it impacts genomes across generations is largely unexplored. We propose that genomes can rearrange via circular intermediates across generations and show that up to 6% of a mammalian genome can have changed gene order through eccDNA.</description><subject>Animals</subject><subject>deletion</subject><subject>DNA, Circular - genetics</subject><subject>eccDNA</subject><subject>evolution</subject><subject>mammal</subject><subject>Mammals - genetics</subject><subject>meiosis</subject><subject>synteny</subject><subject>transposition</subject><issn>0968-0004</issn><issn>1362-4326</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2023</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kDtPwzAURi0EglL4AwzII0vCtZM4DkJCVctLqmCB2bKdG-oqj2Inlfj3pCowMt3lfEe6h5ALBjEDJq7Xce9MiDlwHkMRA4MDMmGJ4FGacHFIJlAIGQFAekJOQ1gDsCzPs2NyMjIS0kJMyM3CldQ6b4dae7p4mdGw0huk_Qopbrt66F3X0q6ijW4aXTvd0g9suwbD3Rk5qnQd8PznTsn7w_3b_Clavj4-z2fLyCYZ6yNhZZYymUDJZJkIkwlRMIsmzxM0JklRl8xUUoPJJS-KLDNSF7LKRZVCCTkkU3K192589zlg6FXjgsW61i12Q1A85zIVmQQxonyPWt-F4LFSG-8a7b8UA7VrptZq10ztmiko1NhsHF3--AfTYPk3-Y00Ard7AMcvtw69CtZha7F0Hm2vys795_8GUFJ7hA</recordid><startdate>202304</startdate><enddate>202304</enddate><creator>Holt, Sylvester</creator><creator>Arrey, Gerard</creator><creator>Regenberg, Birgitte</creator><general>Elsevier Ltd</general><scope>6I.</scope><scope>AAFTH</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0003-4996-7012</orcidid></search><sort><creationdate>202304</creationdate><title>Did circular DNA shape the evolution of mammalian genomes?</title><author>Holt, Sylvester ; Arrey, Gerard ; Regenberg, Birgitte</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c351t-6c8541830d18d36b56691ceb773ebb34ead1bf8a0b7829955b8a98f76f40d0703</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2023</creationdate><topic>Animals</topic><topic>deletion</topic><topic>DNA, Circular - genetics</topic><topic>eccDNA</topic><topic>evolution</topic><topic>mammal</topic><topic>Mammals - genetics</topic><topic>meiosis</topic><topic>synteny</topic><topic>transposition</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Holt, Sylvester</creatorcontrib><creatorcontrib>Arrey, Gerard</creatorcontrib><creatorcontrib>Regenberg, Birgitte</creatorcontrib><collection>ScienceDirect Open Access Titles</collection><collection>Elsevier:ScienceDirect:Open Access</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Trends in biochemical sciences (Amsterdam. Regular ed.)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Holt, Sylvester</au><au>Arrey, Gerard</au><au>Regenberg, Birgitte</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Did circular DNA shape the evolution of mammalian genomes?</atitle><jtitle>Trends in biochemical sciences (Amsterdam. Regular ed.)</jtitle><addtitle>Trends Biochem Sci</addtitle><date>2023-04</date><risdate>2023</risdate><volume>48</volume><issue>4</issue><spage>317</spage><epage>320</epage><pages>317-320</pages><issn>0968-0004</issn><eissn>1362-4326</eissn><abstract>Extrachromosomal circular DNA (eccDNA) can shape the genomes of somatic cells, but how it impacts genomes across generations is largely unexplored. We propose that genomes can rearrange via circular intermediates across generations and show that up to 6% of a mammalian genome can have changed gene order through eccDNA.</abstract><cop>England</cop><pub>Elsevier Ltd</pub><pmid>36280496</pmid><doi>10.1016/j.tibs.2022.09.010</doi><tpages>4</tpages><orcidid>https://orcid.org/0000-0003-4996-7012</orcidid><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0968-0004 |
| ispartof | Trends in biochemical sciences (Amsterdam. Regular ed.), 2023-04, Vol.48 (4), p.317-320 |
| issn | 0968-0004 1362-4326 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_2728465806 |
| source | MEDLINE; ScienceDirect Journals (5 years ago - present) |
| subjects | Animals deletion DNA, Circular - genetics eccDNA evolution mammal Mammals - genetics meiosis synteny transposition |
| title | Did circular DNA shape the evolution of mammalian genomes? |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-06T23%3A33%3A25IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Did%20circular%20DNA%20shape%20the%20evolution%20of%20mammalian%20genomes?&rft.jtitle=Trends%20in%20biochemical%20sciences%20(Amsterdam.%20Regular%20ed.)&rft.au=Holt,%20Sylvester&rft.date=2023-04&rft.volume=48&rft.issue=4&rft.spage=317&rft.epage=320&rft.pages=317-320&rft.issn=0968-0004&rft.eissn=1362-4326&rft_id=info:doi/10.1016/j.tibs.2022.09.010&rft_dat=%3Cproquest_cross%3E2728465806%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2728465806&rft_id=info:pmid/36280496&rft_els_id=S0968000422002699&rfr_iscdi=true |