Effect of time to pre‐emptive transjugular intrahepatic portosystemic shunt on patient outcome, a UK multicentre cohort study

Summary Background Pre‐emptive transjugular intrahepatic portosystemic shunt (pTIPSS) should be considered within 72 hours following acute oesophageal variceal bleeding. However, recent studies highlight the difficulty in providing pTIPSS within this narrow timeframe. Delaying pTIPSS beyond 72 hours...

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Veröffentlicht in:	Alimentary pharmacology & therapeutics 2023-01, Vol.57 (2), p.237-244
Hauptverfasser:	Dunne, Philip, Finkel, Jemima, Khan, Faisal, Lachlan, Neil, Patch, David, Tripathi, Dhiraj, Stanley, Adrian, Hayes, Peter
Format:	Artikel
Sprache:	eng
Schlagworte:	Ascites Cohort analysis Cohort Studies Endoscopy Esophageal and Gastric Varices - complications Gastrointestinal Hemorrhage - complications Gastrointestinal Hemorrhage - surgery Hepatic encephalopathy Humans Liver Cirrhosis - complications Liver diseases Liver Failure - etiology Portasystemic Shunt, Transjugular Intrahepatic - adverse effects Survival Treatment Outcome United Kingdom - epidemiology
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Zusammenfassung:	Summary Background Pre‐emptive transjugular intrahepatic portosystemic shunt (pTIPSS) should be considered within 72 hours following acute oesophageal variceal bleeding. However, recent studies highlight the difficulty in providing pTIPSS within this narrow timeframe. Delaying pTIPSS beyond 72 hours has not been studied. Aim To determine if the time taken to perform pTIPSS alters patient outcome. Method Patients referred to 4 UK tertiary centres for pTIPSS between 01 January 2010 and 31 December 2018 were included. Time from endoscopy to pTIPSS was recorded and pre‐defined clinically relevant outcomes were observed relative to two groups: early pTIPSS (
ISSN:	0269-2813 1365-2036
DOI:	10.1111/apt.17252