Preventive effects of preoperative ramelteon on postoperative delirium in Asian elderly population: A randomized, double-blind, placebo-controlled trial, and a systematic review and meta-analysis
•RCT was performed to test whether low-dose ramelteon reduces postoperative delirium.•We ran Asian meta-analysis of RCTs for ramelteon effects on postoperative delirium.•The meta-analysis showed ramelteon reduced postoperative delirium in Asian elderly.
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| Veröffentlicht in: | Asian journal of psychiatry 2022-12, Vol.78, p.103282-103282, Article 103282 |
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| container_end_page | 103282 |
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| container_title | Asian journal of psychiatry |
| container_volume | 78 |
| creator | Tanifuji, Takaki Otsuka, Ikuo Okazaki, Satoshi Horai, Tadasu So, Ryuhei Shiroiwa, Kyoichi Mouri, Kentaro Tanaka, Motofumi Ohmoto, Nobuko Sora, Ichiro Hirai, Midori Fukumoto, Takumi Ku, Yonson Hishimoto, Akitoyo |
| description | •RCT was performed to test whether low-dose ramelteon reduces postoperative delirium.•We ran Asian meta-analysis of RCTs for ramelteon effects on postoperative delirium.•The meta-analysis showed ramelteon reduced postoperative delirium in Asian elderly. |
| doi_str_mv | 10.1016/j.ajp.2022.103282 |
| format | Article |
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| identifier | ISSN: 1876-2018 |
| ispartof | Asian journal of psychiatry, 2022-12, Vol.78, p.103282-103282, Article 103282 |
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| language | eng |
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| source | MEDLINE; Elsevier ScienceDirect Journals |
| subjects | Aged Asian population Delirium - prevention & control Double-Blind Method Humans Indenes - therapeutic use Melatonin Meta-analysis Postoperative delirium Randomized controlled trial Randomized Controlled Trials as Topic |
| title | Preventive effects of preoperative ramelteon on postoperative delirium in Asian elderly population: A randomized, double-blind, placebo-controlled trial, and a systematic review and meta-analysis |
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