Trial of Thrombectomy 6 to 24 Hours after Stroke Due to Basilar-Artery Occlusion

In a Chinese trial, endovascular thrombectomy at 6 to 24 hours led to more good outcomes than standard care but also to more cerebral hemorrhages. Approximately 20% of patients received intravenous thrombolysis.

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Veröffentlicht in:	The New England journal of medicine 2022-10, Vol.387 (15), p.1373-1384
Hauptverfasser:	Jovin, Tudor G., Li, Chuanhui, Wu, Longfei, Wu, Chuanjie, Chen, Jian, Jiang, Changchun, Shi, Zhonghua, Gao, Zongen, Song, Cunfeng, Chen, Wenhuo, Peng, Ya, Yao, Chen, Wei, Ming, Li, Tong, Wei, Liping, Xiao, Guodong, Yang, Hua, Ren, Ming, Duan, Jiangang, Liu, Xinfeng, Yang, Qingwu, Liu, Yuxiu, Zhu, Qingfeng, Shi, Wanchao, Zhu, Qiyi, Li, Xiaobo, Guo, Zaiyu, Yang, Qi, Hou, Chengbei, Zhao, Wenbo, Ma, Qingfeng, Zhang, Yunzhou, Jiao, Liqun, Zhang, Hongqi, Liebeskind, David S., Liang, Hui, Jadhav, Ashutosh P., Wen, Changming, Brown, Scott, Zhu, Liangfu, Ye, Huawei, Ribo, Marc, Chang, Mingze, Song, Haiqing, Chen, Jun, Ji, Xunming
Format:	Artikel
Sprache:	eng
Schlagworte:	Arterial Occlusive Diseases - complications Arterial Occlusive Diseases - drug therapy Arterial Occlusive Diseases - mortality Arterial Occlusive Diseases - surgery Basilar Artery - drug effects Basilar Artery - surgery Brain Ischemia - drug therapy Brain Ischemia - etiology Brain Ischemia - mortality Brain Ischemia - surgery Cardiovascular system Cerebral blood flow Disability Evaluation Emergency Medicine Endovascular Procedures - adverse effects Endovascular Procedures - methods Fibrinolytic Agents - adverse effects Fibrinolytic Agents - therapeutic use Hemorrhage Humans Intracranial Hemorrhages - chemically induced Intracranial Hemorrhages - etiology Ischemia Magnetic resonance imaging Medical imaging Mortality Neuroimaging Neurology Neurosurgery Patients Radiology Radiology General Recovery of Function Stroke Stroke - drug therapy Stroke - etiology Stroke - mortality Stroke - surgery Thrombectomy - adverse effects Thrombectomy - methods Thrombolysis Time Factors Treatment Outcome Veins & arteries
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Beschreibung
Zusammenfassung:	In a Chinese trial, endovascular thrombectomy at 6 to 24 hours led to more good outcomes than standard care but also to more cerebral hemorrhages. Approximately 20% of patients received intravenous thrombolysis.
ISSN:	0028-4793 1533-4406 1533-4406
DOI:	10.1056/NEJMoa2207576