Inter-semispinal plane (ISP) block for postoperative analgesia following cervical spine surgery: A prospective randomized controlled trial

We evaluated the perioperative analgesic effects of the inter-semispinal plane (ISP) block in patients undergoing posterior cervical spine surgery. Prospective, randomized, controlled, double-blinded trial. Operating room and surgical ward. 60 patients aged 18–60 years of either gender, ASA I-II, undergoing elective posterior cervical spine surgery. Patients were randomly assigned into a control group (general anesthesia only), ISP group received bilateral ultrasound guided ISP block at the level of C5 using 20 ml bupivacaine 0.25% on each side. Visual analog scale (VAS), intraoperative fentanyl and 24 h postoperative pethidine consumptions and time to first rescue analgesic request were documented. The median (quartiles) of 24 h postoperative rescue pethidine consumption was significantly lower in the ISP group [0 (0–46.25) mg] compared to that of the control group [143 (116.75–169.00) mg]; P