Diabetes-related antibody-testing is a valuable screening tool for identifying monogenic diabetes – A survey from the worldwide SWEET registry
To evaluate access to screening tools for monogenic diabetes in paediatric diabetes centres across the world and its impact on diagnosis and clinical outcomes of children and youth with genetic forms of diabetes. 79 centres from the SWEET diabetes registry including 53,207 children with diabetes par...
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Veröffentlicht in: | Diabetes research and clinical practice 2022-10, Vol.192, p.110110-110110, Article 110110 |
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Format: | Artikel |
Sprache: | eng |
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Zusammenfassung: | To evaluate access to screening tools for monogenic diabetes in paediatric diabetes centres across the world and its impact on diagnosis and clinical outcomes of children and youth with genetic forms of diabetes.
79 centres from the SWEET diabetes registry including 53,207 children with diabetes participated in a survey on accessibility and use of diabetes related antibodies, c-peptide and genetic testing.
73, 63 and 62 participating centres had access to c-peptide, antibody and genetic testing, respectively. Access to antibody testing was associated with higher proportion of patients with rare forms of diabetes identified with monogenic diabetes (54 % versus 17 %, p = 0.01), lower average whole clinic HbA1c (7.7[Q1,Q2: 7.3–8.0]%/61[56–64]mmol/mol versus 9.2[8.6–10.0]%/77[70–86]mmol/mol, p |
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ISSN: | 0168-8227 1872-8227 |
DOI: | 10.1016/j.diabres.2022.110110 |