First molecular evidence of Coxiella burnetii in bats from Colombia

Coxiella burnetii is the etiologic agent of Q fever, a zoonotic infectious disease of worldwide distribution that has a wide clinical spectrum. Transmission of C. burnetii occurs by inhalation of contaminated secretions and excreta of infected animal species, particularly goats, cattle and sheep. Activities associated with livestock contact represent the principal risk factor, however participation of wildlife reservoirs is underestimated. Thus, the aim of this study was to evaluate the presence of C. burnetii DNA in blood from bats. Molecular analyses using a qPCR targeting the IS1111 specific gene to detect DNA of C. burnetii in blood samples from 126 bats captured in the Macaregua cave, Colombia, between 2014, 2015 and 2018 were performed. Molecular evidence of C. burnetii was found in 6.3%. Results obtained in the present study represent the first detection of C. burnetii among bats in Colombia, suggesting that more studies need to be done in order to determine the role of these animals in the eco-epidemiology of Q fever. •Molecular evidence of Coxiella burnetii presence in bats from Colombia is described for the first time.•Coxiella burnetii was detected from all three bat species examined: C. perspicillata; M. megalophylla and N. tumidirostris.•All three bat species inhabit permanently the sampled cave: The Macaregua cave, Colombia.•Future research must be done to determine the potential role of bats hosts of Coxiella burnetii.