Re-examining the characteristics of pediatric multiple sclerosis in the era of antibody-associated demyelinating syndromes

The discovery of anti-myelin oligodendrocyte glycoprotein (MOG)-IgG and anti-aquaporin 4 (AQP4)-IgG and the observation on certain patients previously diagnosed with multiple sclerosis (MS) actually have an antibody-mediated disease mandated re-evaluation of pediatric MS series. To describe the char...

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Veröffentlicht in:European journal of paediatric neurology 2022-11, Vol.41, p.8-18
Hauptverfasser: Yılmaz, Ünsal, Gücüyener, Kıvılcım, Yavuz, Merve, Öncel, İbrahim, Saltık, Sema, Ünver, Olcay, Yılmaz, Sanem, Erol, İlknur, Öztoprak, Ülkühan, Elitez, Duygu Aykol, Direk, Meltem Çobanoğulları, Bodur, Muhittin, Teber, Serap, Anlar, Banu, Çıtak Kurt, Ayşegül Neşe, Tosun, Ayşe, Özgör, Bilge, Aykol, Duygu, Yıldız, Edibe Pembegül, Yarar, Coşkun, Haspolat, Şenay, İncecik, Faruk, Kutluk, Gültekin, Dundar, Nihal Olgac, Demir, Ercan, Türkdoğan, Dilşad, Yalnızoğlu, Dilek, Akbaş, Salih, Güleç, Ayten, Yılmaz, Deniz, Ayanoğlu, Müge, Kanmaz, Seda, Beşen, Şeyda, Öztürk, Selcan, Yüksel, Deniz, Gürkaş, Esra, Oktay, Seçil, Serin, Hepsen Mine, Karadağ, Meral, Hakkı Akbeyaz, İsmail, Yiş, Uluç, Polat, Burçin Gönüllü, Okan, Mehmet Sait, Bektaş, Ömer, Orgun, Leman Tekin, Günbey, Ceren, Gültutan, Pembe, Aksoy, Erhan, Akyüz, Gülcan, Tekgül, Hasan, Kürekçi, Fulya, Kurul, A. Semra Hız, Çarman, Kürşat Bora, Duman, Özgür, Kömür, Mustafa, Yıldırım, Miraç, Alıcı, Nurettin, Gümüş, Hakan, Polat, Muzaffer, Konuşkan, Bahadır, Güngör, Olcay, Mert, Gülen Gül, Edizer, Selvinaz, Mıhçı, Filiz, Toker, Rabia Tütüncü, Şahin, Sevim, Gencpinar, Pinar, Yıldırım, Elif, Yüksel, Ersin, Ekici, Arzu, Deniz, Adnan, Yayici Köken, Özlem, Okuyaz, Çetin, Süt, Nurşah Yeniay, Atasoy, Ergin, Yetkin, Mehmet Fatih, Bilgin, Neslihan, Tekin, Hande Gazeteci, Özçelik, Aysima, Türköz, Ayşe Nur, Cavusoglu, Dilek, Özkan, Mehbare, Tekin, Emine, Koç, Habibe, Sarıgeçili, Esra, Sarıtaş, Serdar, Ayça, Senem, Şenoğlu, Mine Çiğdem, Kamaşak, Tülay, Keskin, Filiz, Karaoğlu, Pakize, İpek, Rojan, Acer, Hamit
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Sprache:eng
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Zusammenfassung:The discovery of anti-myelin oligodendrocyte glycoprotein (MOG)-IgG and anti-aquaporin 4 (AQP4)-IgG and the observation on certain patients previously diagnosed with multiple sclerosis (MS) actually have an antibody-mediated disease mandated re-evaluation of pediatric MS series. To describe the characteristics of recent pediatric MS cases by age groups and compare with the cohort established before 2015. Data of pediatric MS patients diagnosed between 2015 and 2021 were collected from 44 pediatric neurology centers across Türkiye. Clinical and paraclinical features were compared between patients with disease onset before 12 years (earlier onset) and ≥12 years (later onset) as well as between our current (2015–2021) and previous (
ISSN:1090-3798
1532-2130
1532-2130
DOI:10.1016/j.ejpn.2022.08.006