Self-assembly of an MRI responsive agent under physiological conditions provides an extended time window for in vivo imaging

Self-assembly of an MRI responsive agent under physiological conditions provides an extended time window for in vivo imaging

An MRI-responsive agent that spontaneously self-assembles to a large supramolecular structure under physiological conditions was designed. The obtained assembly provides an extended time window for in vivo studies, as demonstrated for a fluorine-19 probe constructed to sense Zn 2+ with 19 F-iCEST MR...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Chemical communications (Cambridge, England) England), 2022-10, Vol.58 (81), p.11410-11413
Hauptverfasser: Tirukoti, Nishanth D., Avram, Liat, Mashiach, Reut, Allouche-Arnon, Hyla, Bar-Shir, Amnon
Format: Artikel
Sprache:eng
Schlagworte:
Fluorine
In vivo methods and tests
Self-assembly
Windows (intervals)
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:An MRI-responsive agent that spontaneously self-assembles to a large supramolecular structure under physiological conditions was designed. The obtained assembly provides an extended time window for in vivo studies, as demonstrated for a fluorine-19 probe constructed to sense Zn 2+ with 19 F-iCEST MRI, in the future.
ISSN:1359-7345
1364-548X
DOI:10.1039/d2cc03126d