Spectrum scores: Toward a better definition of de-escalation

Spectrum scores: Toward a better definition of de-escalation

Spectrum scores measure antimicrobial utilization while also quantifying the spectrum of activity. Accordingly, changes in spectrum score can be used to identify antimicrobial de-escalation. We show that spectrum-score–based de-escalation has a 95.7% positive percentage agreement and 81.6% negative...

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Veröffentlicht in:Infection control and hospital epidemiology 2023-06, Vol.44 (6), p.938-940
Hauptverfasser: Ilges, Daniel T., Ritchie, David J., Krekel, Tamara, Neuner, Elizabeth A., Micek, Scott T.
Format: Artikel
Sprache:eng
Schlagworte:
Agreements
Antibiotics
Antimicrobial agents
Clinical outcomes
Concise Communication
Methods
Patients
Pneumonia
Staphylococcus infections
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Zusammenfassung:Spectrum scores measure antimicrobial utilization while also quantifying the spectrum of activity. Accordingly, changes in spectrum score can be used to identify antimicrobial de-escalation. We show that spectrum-score–based de-escalation has a 95.7% positive percentage agreement and 81.6% negative percentage agreement versus de-escalation defined as stopping either antistaphylococcal or antipseudomonal agents.
ISSN:0899-823X
1559-6834
DOI:10.1017/ice.2022.207