Biochemical Status of Obese Male Adolescents of Different Ethnicity: Discriminant Analysis in the Identification of the Most Informative Indicators

Parameters of the lipid metabolism and lipid peroxidation—antioxidant defense system in male adolescents with obesity, representatives of European and Mongoloid ethnicity were evaluated. Discriminant analysis revealed the most informative biochemical parameters for obese male adolescents: glutathion...

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Veröffentlicht in:Bulletin of experimental biology and medicine 2022-08, Vol.173 (4), p.459-463
Hauptverfasser: Darenskaya, M. A., Rychkova, L. V., Kolesnikov, S. I., Semenova, N. V., Nikitina, O. A., Brichagina, A. S., Mikhalevich, I. M., Kolesnikova, L. I.
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Sprache:eng
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Zusammenfassung:Parameters of the lipid metabolism and lipid peroxidation—antioxidant defense system in male adolescents with obesity, representatives of European and Mongoloid ethnicity were evaluated. Discriminant analysis revealed the most informative biochemical parameters for obese male adolescents: glutathione-S-transferase, VLDL cholesterol, glutathione peroxidase, reduced glutathione, and SOD activity for obese male Caucasian adolescents and glutathione-S-transferase, VLDL cholesterol, α-tocopherol, and glutathione peroxidase for Mongoloids obese male adolescents. The use of discriminant analysis allows implementing a differentiated ethnicity-oriented approach to prescribing antioxidant drugs in the complex therapy of obesity.
ISSN:0007-4888
1573-8221
DOI:10.1007/s10517-022-05579-z