The role of glutathione conjugation on the transcellular transport process of PEGylated liposomes across the blood brain barrier

[Display omitted] Notwithstanding the growing evidence of improved drug delivery efficiency to the brain by ligand modification of PEGylated liposomes, the comprehensive knowledge of their transport processes and payload across the BBB is yet to be revealed. Herein, this study sought to understand t...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	International journal of pharmaceutics 2022-10, Vol.626, p.122152-122152, Article 122152
Hauptverfasser:	Reginald-Opara, Joy N., Tang, Mingtan, Svirskis, Darren, Chamley, Larry, Wu, Zimei
Format:	Artikel
Sprache:	eng
Schlagworte:	Brain distribution Exocytosis Glutathione (GSH)-liposomes Human brain microvascular endothelial cells In vitro BBB model Transcytosis
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!