Strategies for persistent retention of macromolecules and nanoparticles in the blood circulation

The enhanced permeability and retention (EPR) effect has been the gold standard in developing drug delivery systems for passive tumor targeting. Although the importance of this concept remains unchanged, some controversies have arisen. In this review, various strategies for tumor targeting using mac...

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Veröffentlicht in:	Journal of controlled release 2022-10, Vol.350, p.486-493
Hauptverfasser:	Takakura, Yoshinobu, Takahashi, Yuki
Format:	Artikel
Sprache:	eng
Schlagworte:	EPR effect Macromolecules Nanoparticles Small extracellular vesicles Tumor targeting
Online-Zugang:	Volltext
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