Factors affecting prognosis in hepatocellular carcinoma patients post-transarterial chemoembolization

Background To evaluate the factors influencing the achievement of a sustained complete response (CR) and overall survival (OS) in hepatocellular carcinoma (HCC) patients undergoing transarterial chemoembolization (TACE). Methods We retrospectively reviewed the records of HCC patients who underwent T...

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Veröffentlicht in:Indian journal of gastroenterology 2022-08, Vol.41 (4), p.352-361
Hauptverfasser: Prateepchaiboon, Tanaporn, Chang, Arunchai, Pungpipattrakul, Nuttanit, Akarapatima, Keerati, Rattanasupar, Attapon, Songjamrat, Apiradee, Pakdeejit, Songklod, Piratvisuth, Teerha
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Sprache:eng
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Zusammenfassung:Background To evaluate the factors influencing the achievement of a sustained complete response (CR) and overall survival (OS) in hepatocellular carcinoma (HCC) patients undergoing transarterial chemoembolization (TACE). Methods We retrospectively reviewed the records of HCC patients who underwent TACE as the first modality of treatment between 2014 and 2019. We investigated the factors affecting sustained CR (no recurrence within 6 months) and OS (time from diagnosis until either death or last follow-up). Results The study enrolled 161 patients; 159 (98.8%) had cirrhosis. Post-TACE, 19.9% (32/161) achieved sustained CR. In the multivariate analysis, a tumor size  100 ng/mL (HR 2.082; p  
ISSN:0254-8860
0975-0711
DOI:10.1007/s12664-021-01227-y