Maternal and zygotic ZFP57 regulate coronary vascular formation and myocardium maturation in mouse embryo

Background Genomic and epigenomic dynamics both play critical roles during embryogenesis. Zfp57 maintains genomic imprinting with both maternal and zygotic functions. In our previous study, we found that maternal and zygotic Zfp57 modulate NOTCH signaling during cardiac development. In this study, w...

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Veröffentlicht in:	Developmental dynamics 2024-01, Vol.253 (1), p.144-156
Hauptverfasser:	Zhao, Junzheng, Zhao, Jingjie
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals cardiac development Cardiomyopathy Cardiovascular system coronary vasculature DNA Methylation Embryogenesis Endothelial cells Endothelial Cells - metabolism Genomic imprinting Heart Maturation Mice Mutants Myocardium Myocardium - metabolism noncompaction Repressor Proteins - genetics ZFP57
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