Pseudo-Isolated α‑Helix Platform for the Recognition of Deep and Narrow Targets

Although interest in stabilized α-helical peptides as next-generation therapeutics for modulating biomolecular interfaces is increasing, peptides have limited functionality and stability due to their small size. In comparison, α-helical ligands based on proteins can make steric clash with targets du...

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Veröffentlicht in:	Journal of the American Chemical Society 2022-08, Vol.144 (34), p.15519-15528
Hauptverfasser:	Kim, Dong-in, Han, So-hee, Park, Hahnbeom, Choi, Sehwan, Kaur, Mandeep, Hwang, Euimin, Han, Seong-jae, Ryu, Jung-yeon, Cheong, Hae-Kap, Barnwal, Ravi Pratap, Lim, Yong-beom
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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