Unbiased matchmaking

Unbiased matchmaking

Elucidating the interactions between serum protein-bound nanoparticles and cell-surface receptors typically operates on a per protein–receptor interaction basis. Integration of omic approaches for testing thousands of interactions unbiasedly reveals important interactions that drive cellular uptake...

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Veröffentlicht in:Nature chemical biology 2022-09, Vol.18 (9), p.921-923
Hauptverfasser: Chan, Cecilia Ka Wing, Lau, Sze Ho Gwyneth, Choi, Chung Hang Jonathan
Format: Artikel
Sprache:eng
Schlagworte:
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Apolipoproteins
Biochemical Engineering
Biochemistry
Biology
Bioorganic Chemistry
Cancer
Cell Biology
Cell surface
Chemistry
Chemistry and Materials Science
Chemistry/Food Science
CRISPR
Genes
Genomes
Hypotheses
Nanoparticles
News & Views
news-and-views
Proteins
Receptors
Serum proteins
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Beschreibung
Zusammenfassung:Elucidating the interactions between serum protein-bound nanoparticles and cell-surface receptors typically operates on a per protein–receptor interaction basis. Integration of omic approaches for testing thousands of interactions unbiasedly reveals important interactions that drive cellular uptake of nanoparticles.
ISSN:1552-4450
1552-4469
DOI:10.1038/s41589-022-01108-1