Management of COVID-19 Infection-Associated Flare in an Adolescent with Pediatric Acute Neuropsychiatric Syndrome and Obsessive-Compulsive Disorder

Parents report that K. was able to catch up on his developmental milestones after receiving intensive physical, occupational, and speech therapy. Educational History K. had been enrolled in the life skills and education for students with autism and pervasive behavioral challenges program at age 2 years that reportedly facilitated a relatively smooth transition to kindergarten and elementary school. Predisposing factors included a history of premature birth in the context of suspected intrauterine radiation exposure and a protracted NICU stay, and delays in fine motor and social development. Family history of autoimmune disease and psychiatric disorder Suspected intrauterine exposure to radiation Axis V: 31 on initial encounter; 70 on latest follow-up Treatment Course During initial follow-up visits at 9 years of age, K. showed gradual improvement in anxiety, obsessions, and compulsions, as sertraline was titrated up to 75 mg daily within 4 weeks and maintained for ∼6 months.