Angioedema severity and impact on quality of life: Chronic histaminergic angioedema versus chronic spontaneous urticaria

Clinical Implications The impact of angioedema on quality of life is greater for patients with angioedema associated with chronic spontaneous urticaria than chronic histaminergic angioedema. [...]this term reflects the chronic and recurrent course of the disease. [...]we propose that the term CHA be internationally discussed in the following guidelines. [...]a new urticaria activity score that incorporates AAS items may be useful. [...]the impact on QoL is subject to patients’ individual interpretations of symptoms.