Passing down maternal dietary memories through lncRNAs

Parental diet is known to influence the offspring in an intergenerational manner, and this has been implicated in species adaptation and general health. Recent studies highlight the role of maternal long noncoding RNAs (lncRNAs) in serving as one of the 'memories' of maternal diet in regul...

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Veröffentlicht in:	Trends in genetics 2023-02, Vol.39 (2), p.91-93
Hauptverfasser:	Koh, Xin Yi, Pek, Jun Wei
Format:	Artikel
Sprache:	eng
Schlagworte:	Diet intergenerational inheritance long noncoding RNA maternal oocyte RNA, Long Noncoding - genetics RNA, Long Noncoding - metabolism
Online-Zugang:	Volltext
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Beschreibung
Zusammenfassung:	Parental diet is known to influence the offspring in an intergenerational manner, and this has been implicated in species adaptation and general health. Recent studies highlight the role of maternal long noncoding RNAs (lncRNAs) in serving as one of the 'memories' of maternal diet in regulating offspring development and predisposition to metabolic disease.
ISSN:	0168-9525
DOI:	10.1016/j.tig.2022.07.006