A phase transition for chromosome transmission when cells divide

An analysis of chromosomes during mitotic cell division reveals that DNA and associated histone proteins condense through a process called phase transition, which helps them to resist the pushing forces involved in mitosis. A mechanism to prevent microtubules from perforating mitotic chromosomes.

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Veröffentlicht in:Nature (London) 2022-09, Vol.609 (7925), p.35-36
1. Verfasser: Maeshima, Kazuhiro
Format: Artikel
Sprache:eng
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Zusammenfassung:An analysis of chromosomes during mitotic cell division reveals that DNA and associated histone proteins condense through a process called phase transition, which helps them to resist the pushing forces involved in mitosis. A mechanism to prevent microtubules from perforating mitotic chromosomes.
ISSN:0028-0836
1476-4687
DOI:10.1038/d41586-022-01925-3