A comprehensive review of recent advances in the biological activities of quinazolines

Quinazoline heterocycles are critical in the development of medications. Quinazoline derivatives have been intensively researched, providing a wide range of compounds with diverse biological roles. The quinazoline nucleus has garnered a lot of attention in medical chemistry in recent years. It was a...

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Veröffentlicht in:Chemical biology & drug design 2022-11, Vol.100 (5), p.639-655
1. Verfasser: Gomaa, Hesham A. M.
Format: Artikel
Sprache:eng
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Zusammenfassung:Quinazoline heterocycles are critical in the development of medications. Quinazoline derivatives have been intensively researched, providing a wide range of compounds with diverse biological roles. The quinazoline nucleus has garnered a lot of attention in medical chemistry in recent years. It was assumed to be a pharmacophore component in the development of physiologically interesting drugs. This review is an attempt to increase the potential of quinazoline by highlighting a wide range of advancements demonstrated by numerous derivatives of the quinazoline moiety, as well as focusing on diverse pharmacological actions of the quinazoline moiety. This review compiles recent studies on the quinazoline moiety described in the literature by researchers. The quinazoline nucleus has garnered a lot of attention in medical chemistry in recent years. It was assumed to be a pharmacophore component in the development of physiologically interesting drugs. This review provides an in‐depth look at recent advances in the biological activities of quinazolines.
ISSN:1747-0277
1747-0285
DOI:10.1111/cbdd.14129