Hidden epithelial subtypes refine colorectal cancer classification

Hidden epithelial subtypes refine colorectal cancer classification

Using single-cell transcriptomic data, Joanito et al. reveal that colorectal cancers can be defined by the presence of one of two major intrinsic epithelial subtypes, and present a refined molecular classification system for these cancers.

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Bibliographische Detailangaben
Veröffentlicht in:Nature reviews. Cancer 2022-09, Vol.22 (9), p.495-495
1. Verfasser: Willson, Joseph
Format: Artikel
Sprache:eng
Schlagworte:
631/208/212/2019
631/67/1504/1885
Biomedical and Life Sciences
Biomedicine
Cancer Research
Colorectal cancer
Colorectal carcinoma
Research Highlight
Transcriptomics
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Zusammenfassung:Using single-cell transcriptomic data, Joanito et al. reveal that colorectal cancers can be defined by the presence of one of two major intrinsic epithelial subtypes, and present a refined molecular classification system for these cancers.
ISSN:1474-175X
1474-1768
DOI:10.1038/s41568-022-00501-1