Anti‐Müllerian hormone as an endocrine biomarker of reproductive longevity and assessment of single nucleotide polymorphisms in AMH gene of Bos indicus breeds of cattle
Anti‐Müllerian hormone (AMH) is a member of the TGF‐β superfamily produced by follicular granulosa cells in women and cattle and is considered an endocrine biomarker of ovarian follicular reserve. The study examined how age and parity influence serum AMH concentration and investigated the presence o...
Gespeichert in:
| Veröffentlicht in: | Reproduction in domestic animals 2022-11, Vol.57 (11), p.1450-1464 |
|---|---|
| Hauptverfasser: | , , , , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 1464 |
|---|---|
| container_issue | 11 |
| container_start_page | 1450 |
| container_title | Reproduction in domestic animals |
| container_volume | 57 |
| creator | Ramesha, Kerekoppa P. Jeyakumar, Sakthivel Mall, Shweta Vedamurthy, Gowdar Veerappa Kumaresan, Arumugam Devadasn, Milton Joel Kataktalware, Mukund A. Arul, Dhayalan Das, Dayal Nitai Manimaran, Ayyasamy |
| description | Anti‐Müllerian hormone (AMH) is a member of the TGF‐β superfamily produced by follicular granulosa cells in women and cattle and is considered an endocrine biomarker of ovarian follicular reserve. The study examined how age and parity influence serum AMH concentration and investigated the presence of single nucleotide polymorphisms in AMH gene in Bos indicus breeds viz Malnad Gidda Amritmahal and Hallikar. All five exons of AMH gene amplified by polymerase chain reaction were subjected to sanger sequencing and identified important SNP and its effects. We observed a highly significant relationship between parity and AMH concentration in Amritmahal cattle, whereas Malnad Gidda and Hallikar breeds did not show a significant difference. We identified one SNP located in exon 5 (rs21402788) with base change A>G, a non‐synonymous mutation resulting in a change in amino acid Q>R and the protein product. It is concluded that AMH level could be considered as an indicator of the ovarian reserve and productive herd life (longevity) irrespective of age/parity, especially in B. indicus breeds of cattle. |
| doi_str_mv | 10.1111/rda.14222 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_2697369108</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2730499583</sourcerecordid><originalsourceid>FETCH-LOGICAL-c3962-16784d16a8a8e824753b0950d6e1e61f38c3e654fea7fdad61ae36bb6a64f3353</originalsourceid><addsrcrecordid>eNp1kcFu1DAQhi1EJZbCgTewxAUOae04cZzj0gJFalUJwdly7MnWxbEXT1K0Nx6B9-AVeuNNeBK8LCek-jKaX9_vsecn5AVnJ7yc0-zMCW_qun5EVrwRfcVawR-TFeuFrGQn1RPyFPGWMd6qrluRn-s4-9_ff1z9ug8BsjeR3qQ8pQjUIC0dRJds9qUffJpM_gKZppFm2ObkFjv7O6AhxQ3c-XlXDK74EBAniPMeRB83AWhcbIA0ewd0m8JuSnl743FC6iNdX13QDZQJBX-T9pLzdkE6ZACHe9WaeQ7wjByNJiA8_1ePyed3bz-dXVSX1-8_nK0vKyt6WVdcdqpxXBplFKi66VoxsL5lTgIHyUehrADZNiOYbnTGSW5AyGGQRjajEK04Jq8O95Yvfl0AZz15tBCCiZAW1LXsOyF7zlRBX_6H3qYlx_I6XXeCNX3fKlGo1wfK5oSYYdTb7Msud5ozvY9Nl9j039gKe3pgv_kAu4dB_fF8fXD8ATP_neg</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2730499583</pqid></control><display><type>article</type><title>Anti‐Müllerian hormone as an endocrine biomarker of reproductive longevity and assessment of single nucleotide polymorphisms in AMH gene of Bos indicus breeds of cattle</title><source>Wiley Online Library Journals Frontfile Complete</source><creator>Ramesha, Kerekoppa P. ; Jeyakumar, Sakthivel ; Mall, Shweta ; Vedamurthy, Gowdar Veerappa ; Kumaresan, Arumugam ; Devadasn, Milton Joel ; Kataktalware, Mukund A. ; Arul, Dhayalan ; Das, Dayal Nitai ; Manimaran, Ayyasamy</creator><creatorcontrib>Ramesha, Kerekoppa P. ; Jeyakumar, Sakthivel ; Mall, Shweta ; Vedamurthy, Gowdar Veerappa ; Kumaresan, Arumugam ; Devadasn, Milton Joel ; Kataktalware, Mukund A. ; Arul, Dhayalan ; Das, Dayal Nitai ; Manimaran, Ayyasamy</creatorcontrib><description>Anti‐Müllerian hormone (AMH) is a member of the TGF‐β superfamily produced by follicular granulosa cells in women and cattle and is considered an endocrine biomarker of ovarian follicular reserve. The study examined how age and parity influence serum AMH concentration and investigated the presence of single nucleotide polymorphisms in AMH gene in Bos indicus breeds viz Malnad Gidda Amritmahal and Hallikar. All five exons of AMH gene amplified by polymerase chain reaction were subjected to sanger sequencing and identified important SNP and its effects. We observed a highly significant relationship between parity and AMH concentration in Amritmahal cattle, whereas Malnad Gidda and Hallikar breeds did not show a significant difference. We identified one SNP located in exon 5 (rs21402788) with base change A>G, a non‐synonymous mutation resulting in a change in amino acid Q>R and the protein product. It is concluded that AMH level could be considered as an indicator of the ovarian reserve and productive herd life (longevity) irrespective of age/parity, especially in B. indicus breeds of cattle.</description><identifier>ISSN: 0936-6768</identifier><identifier>EISSN: 1439-0531</identifier><identifier>DOI: 10.1111/rda.14222</identifier><language>eng</language><publisher>Oxford: Blackwell Publishing Ltd</publisher><subject>AMH gene ; Amino acids ; anti‐Müllerian hormone ; Biomarkers ; Bos indicus cattle ; Bos taurus indicus ; Cattle ; Exons ; Granulosa cells ; Longevity ; Mutation ; Nucleotides ; Ovaries ; Parity ; Polymerase chain reaction ; polymorphism ; reproduction ; sanger sequencing ; Single-nucleotide polymorphism</subject><ispartof>Reproduction in domestic animals, 2022-11, Vol.57 (11), p.1450-1464</ispartof><rights>2022 Wiley‐VCH GmbH.</rights><rights>Copyright © 2022 Wiley‐VCH GmbH</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c3962-16784d16a8a8e824753b0950d6e1e61f38c3e654fea7fdad61ae36bb6a64f3353</citedby><cites>FETCH-LOGICAL-c3962-16784d16a8a8e824753b0950d6e1e61f38c3e654fea7fdad61ae36bb6a64f3353</cites><orcidid>0000-0002-8061-3477</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1111%2Frda.14222$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1111%2Frda.14222$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,776,780,1411,27901,27902,45550,45551</link.rule.ids></links><search><creatorcontrib>Ramesha, Kerekoppa P.</creatorcontrib><creatorcontrib>Jeyakumar, Sakthivel</creatorcontrib><creatorcontrib>Mall, Shweta</creatorcontrib><creatorcontrib>Vedamurthy, Gowdar Veerappa</creatorcontrib><creatorcontrib>Kumaresan, Arumugam</creatorcontrib><creatorcontrib>Devadasn, Milton Joel</creatorcontrib><creatorcontrib>Kataktalware, Mukund A.</creatorcontrib><creatorcontrib>Arul, Dhayalan</creatorcontrib><creatorcontrib>Das, Dayal Nitai</creatorcontrib><creatorcontrib>Manimaran, Ayyasamy</creatorcontrib><title>Anti‐Müllerian hormone as an endocrine biomarker of reproductive longevity and assessment of single nucleotide polymorphisms in AMH gene of Bos indicus breeds of cattle</title><title>Reproduction in domestic animals</title><description>Anti‐Müllerian hormone (AMH) is a member of the TGF‐β superfamily produced by follicular granulosa cells in women and cattle and is considered an endocrine biomarker of ovarian follicular reserve. The study examined how age and parity influence serum AMH concentration and investigated the presence of single nucleotide polymorphisms in AMH gene in Bos indicus breeds viz Malnad Gidda Amritmahal and Hallikar. All five exons of AMH gene amplified by polymerase chain reaction were subjected to sanger sequencing and identified important SNP and its effects. We observed a highly significant relationship between parity and AMH concentration in Amritmahal cattle, whereas Malnad Gidda and Hallikar breeds did not show a significant difference. We identified one SNP located in exon 5 (rs21402788) with base change A>G, a non‐synonymous mutation resulting in a change in amino acid Q>R and the protein product. It is concluded that AMH level could be considered as an indicator of the ovarian reserve and productive herd life (longevity) irrespective of age/parity, especially in B. indicus breeds of cattle.</description><subject>AMH gene</subject><subject>Amino acids</subject><subject>anti‐Müllerian hormone</subject><subject>Biomarkers</subject><subject>Bos indicus cattle</subject><subject>Bos taurus indicus</subject><subject>Cattle</subject><subject>Exons</subject><subject>Granulosa cells</subject><subject>Longevity</subject><subject>Mutation</subject><subject>Nucleotides</subject><subject>Ovaries</subject><subject>Parity</subject><subject>Polymerase chain reaction</subject><subject>polymorphism</subject><subject>reproduction</subject><subject>sanger sequencing</subject><subject>Single-nucleotide polymorphism</subject><issn>0936-6768</issn><issn>1439-0531</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2022</creationdate><recordtype>article</recordtype><recordid>eNp1kcFu1DAQhi1EJZbCgTewxAUOae04cZzj0gJFalUJwdly7MnWxbEXT1K0Nx6B9-AVeuNNeBK8LCek-jKaX9_vsecn5AVnJ7yc0-zMCW_qun5EVrwRfcVawR-TFeuFrGQn1RPyFPGWMd6qrluRn-s4-9_ff1z9ug8BsjeR3qQ8pQjUIC0dRJds9qUffJpM_gKZppFm2ObkFjv7O6AhxQ3c-XlXDK74EBAniPMeRB83AWhcbIA0ewd0m8JuSnl743FC6iNdX13QDZQJBX-T9pLzdkE6ZACHe9WaeQ7wjByNJiA8_1ePyed3bz-dXVSX1-8_nK0vKyt6WVdcdqpxXBplFKi66VoxsL5lTgIHyUehrADZNiOYbnTGSW5AyGGQRjajEK04Jq8O95Yvfl0AZz15tBCCiZAW1LXsOyF7zlRBX_6H3qYlx_I6XXeCNX3fKlGo1wfK5oSYYdTb7Msud5ozvY9Nl9j039gKe3pgv_kAu4dB_fF8fXD8ATP_neg</recordid><startdate>202211</startdate><enddate>202211</enddate><creator>Ramesha, Kerekoppa P.</creator><creator>Jeyakumar, Sakthivel</creator><creator>Mall, Shweta</creator><creator>Vedamurthy, Gowdar Veerappa</creator><creator>Kumaresan, Arumugam</creator><creator>Devadasn, Milton Joel</creator><creator>Kataktalware, Mukund A.</creator><creator>Arul, Dhayalan</creator><creator>Das, Dayal Nitai</creator><creator>Manimaran, Ayyasamy</creator><general>Blackwell Publishing Ltd</general><scope>AAYXX</scope><scope>CITATION</scope><scope>7QO</scope><scope>8FD</scope><scope>FR3</scope><scope>P64</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0002-8061-3477</orcidid></search><sort><creationdate>202211</creationdate><title>Anti‐Müllerian hormone as an endocrine biomarker of reproductive longevity and assessment of single nucleotide polymorphisms in AMH gene of Bos indicus breeds of cattle</title><author>Ramesha, Kerekoppa P. ; Jeyakumar, Sakthivel ; Mall, Shweta ; Vedamurthy, Gowdar Veerappa ; Kumaresan, Arumugam ; Devadasn, Milton Joel ; Kataktalware, Mukund A. ; Arul, Dhayalan ; Das, Dayal Nitai ; Manimaran, Ayyasamy</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3962-16784d16a8a8e824753b0950d6e1e61f38c3e654fea7fdad61ae36bb6a64f3353</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2022</creationdate><topic>AMH gene</topic><topic>Amino acids</topic><topic>anti‐Müllerian hormone</topic><topic>Biomarkers</topic><topic>Bos indicus cattle</topic><topic>Bos taurus indicus</topic><topic>Cattle</topic><topic>Exons</topic><topic>Granulosa cells</topic><topic>Longevity</topic><topic>Mutation</topic><topic>Nucleotides</topic><topic>Ovaries</topic><topic>Parity</topic><topic>Polymerase chain reaction</topic><topic>polymorphism</topic><topic>reproduction</topic><topic>sanger sequencing</topic><topic>Single-nucleotide polymorphism</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Ramesha, Kerekoppa P.</creatorcontrib><creatorcontrib>Jeyakumar, Sakthivel</creatorcontrib><creatorcontrib>Mall, Shweta</creatorcontrib><creatorcontrib>Vedamurthy, Gowdar Veerappa</creatorcontrib><creatorcontrib>Kumaresan, Arumugam</creatorcontrib><creatorcontrib>Devadasn, Milton Joel</creatorcontrib><creatorcontrib>Kataktalware, Mukund A.</creatorcontrib><creatorcontrib>Arul, Dhayalan</creatorcontrib><creatorcontrib>Das, Dayal Nitai</creatorcontrib><creatorcontrib>Manimaran, Ayyasamy</creatorcontrib><collection>CrossRef</collection><collection>Biotechnology Research Abstracts</collection><collection>Technology Research Database</collection><collection>Engineering Research Database</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>Reproduction in domestic animals</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Ramesha, Kerekoppa P.</au><au>Jeyakumar, Sakthivel</au><au>Mall, Shweta</au><au>Vedamurthy, Gowdar Veerappa</au><au>Kumaresan, Arumugam</au><au>Devadasn, Milton Joel</au><au>Kataktalware, Mukund A.</au><au>Arul, Dhayalan</au><au>Das, Dayal Nitai</au><au>Manimaran, Ayyasamy</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Anti‐Müllerian hormone as an endocrine biomarker of reproductive longevity and assessment of single nucleotide polymorphisms in AMH gene of Bos indicus breeds of cattle</atitle><jtitle>Reproduction in domestic animals</jtitle><date>2022-11</date><risdate>2022</risdate><volume>57</volume><issue>11</issue><spage>1450</spage><epage>1464</epage><pages>1450-1464</pages><issn>0936-6768</issn><eissn>1439-0531</eissn><abstract>Anti‐Müllerian hormone (AMH) is a member of the TGF‐β superfamily produced by follicular granulosa cells in women and cattle and is considered an endocrine biomarker of ovarian follicular reserve. The study examined how age and parity influence serum AMH concentration and investigated the presence of single nucleotide polymorphisms in AMH gene in Bos indicus breeds viz Malnad Gidda Amritmahal and Hallikar. All five exons of AMH gene amplified by polymerase chain reaction were subjected to sanger sequencing and identified important SNP and its effects. We observed a highly significant relationship between parity and AMH concentration in Amritmahal cattle, whereas Malnad Gidda and Hallikar breeds did not show a significant difference. We identified one SNP located in exon 5 (rs21402788) with base change A>G, a non‐synonymous mutation resulting in a change in amino acid Q>R and the protein product. It is concluded that AMH level could be considered as an indicator of the ovarian reserve and productive herd life (longevity) irrespective of age/parity, especially in B. indicus breeds of cattle.</abstract><cop>Oxford</cop><pub>Blackwell Publishing Ltd</pub><doi>10.1111/rda.14222</doi><tpages>15</tpages><orcidid>https://orcid.org/0000-0002-8061-3477</orcidid></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0936-6768 |
| ispartof | Reproduction in domestic animals, 2022-11, Vol.57 (11), p.1450-1464 |
| issn | 0936-6768 1439-0531 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_2697369108 |
| source | Wiley Online Library Journals Frontfile Complete |
| subjects | AMH gene Amino acids anti‐Müllerian hormone Biomarkers Bos indicus cattle Bos taurus indicus Cattle Exons Granulosa cells Longevity Mutation Nucleotides Ovaries Parity Polymerase chain reaction polymorphism reproduction sanger sequencing Single-nucleotide polymorphism |
| title | Anti‐Müllerian hormone as an endocrine biomarker of reproductive longevity and assessment of single nucleotide polymorphisms in AMH gene of Bos indicus breeds of cattle |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-08T10%3A43%3A25IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Anti%E2%80%90M%C3%BCllerian%20hormone%20as%20an%20endocrine%20biomarker%20of%20reproductive%20longevity%20and%20assessment%20of%20single%20nucleotide%20polymorphisms%20in%20AMH%20gene%20of%20Bos%20indicus%20breeds%20of%20cattle&rft.jtitle=Reproduction%20in%20domestic%20animals&rft.au=Ramesha,%20Kerekoppa%20P.&rft.date=2022-11&rft.volume=57&rft.issue=11&rft.spage=1450&rft.epage=1464&rft.pages=1450-1464&rft.issn=0936-6768&rft.eissn=1439-0531&rft_id=info:doi/10.1111/rda.14222&rft_dat=%3Cproquest_cross%3E2730499583%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2730499583&rft_id=info:pmid/&rfr_iscdi=true |