Preoperative Liver Stiffness is Associated With Hospital Length of Stay After Cardiac Surgery

Risk assessment models for cardiac surgery do not account for the degrees of liver dysfunction. Ultrasound shear-wave elastography measures liver stiffness (LSM), a quantitative measurement related to fibrosis, congestion, and inflammation. The authors hypothesized that preoperative liver stiffness...

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Veröffentlicht in:Journal of cardiothoracic and vascular anesthesia 2022-11, Vol.36 (11), p.4093-4099
Hauptverfasser: Suffredini, Giancarlo, Slowey, Charlie, Sun, Junfeng, Gao, Wei Dong, Choi, Chun (Dan) W., Aziz, Hamza, Kilic, Ahmet, Schena, Stefano, Lawton, Jennifer, Hamilton, James Peter, Dodd-o, Jeffrey M.
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Sprache:eng
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Zusammenfassung:Risk assessment models for cardiac surgery do not account for the degrees of liver dysfunction. Ultrasound shear-wave elastography measures liver stiffness (LSM), a quantitative measurement related to fibrosis, congestion, and inflammation. The authors hypothesized that preoperative liver stiffness would be associated with hospital length of stay after cardiac surgery. Prospective observational study. University hospital, single center. One hundred five adult patients undergoing nonemergent cardiac surgery. Preoperative liver stiffness measured by ultrasound elastography. The associations were analyzed using linear mixed models, with adjustments for preoperative variables, duration of cardiopulmonary bypass, and type of surgery. Median liver stiffness was 6.4 kPa (range, 4.1-18.6 kPa). The median length of hospital stay was 6 days (range, 3-18 d). Each unit increase in liver stiffness, treated as a continuous variable, was associated with an increase of 0.32 ± 0.10 days in the hospital (p = 0.002). When treated as a categorical variable (
ISSN:1053-0770
1532-8422
DOI:10.1053/j.jvca.2022.06.028