Black patients and women have reduced access to liver transplantation for alcohol-associated liver disease

Although sex and racial disparities for liver transplantation (LT) are known, it is unclear if disparities exist for patients with alcohol-associated liver disease (ALD). We aimed to compare sex and racial/ethnic differences in mortality, LT listing, and LT rates in patients with and without ALD. We...

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Veröffentlicht in:Liver transplantation 2023-03, Vol.29 (3), p.259-267
Hauptverfasser: Kaplan, Alyson, Wahid, Nabeel, Fortune, Brett E, Verna, Elizabeth, Halazun, Karim, Samstein, Benjamin, Brown, Jr, Robert S, Rosenblatt, Russell
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Sprache:eng
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Zusammenfassung:Although sex and racial disparities for liver transplantation (LT) are known, it is unclear if disparities exist for patients with alcohol-associated liver disease (ALD). We aimed to compare sex and racial/ethnic differences in mortality, LT listing, and LT rates in patients with and without ALD. We analyzed patients who were listed for LT and/or died of end-stage liver disease (ESLD) between 2014 and 2018 using the United Network for Organ Sharing Standard Transplant Analysis and Research and Centers for Disease Control and Prevention Wide-ranging OnLine Data for Epidemiologic Research databases, respectively. Patients with ALD were compared with non-ALD patients. Our primary outcome was the ratio of listings for LT to deaths from ESLD-listing-to-death ratio (LDR)-a previously derived metric to assess access to the waiting list. Differences between sex and race/ethnicity were analyzed with chi-square tests and multivariable linear regression. There were 65,588 deaths and 16,133 listings for ALD compared with 75,020 deaths and 40,194 listings for non-ALD. LDR was lower for ALD (0.25 vs. 0.54; p
ISSN:1527-6465
1527-6473
DOI:10.1002/lt.26544