Effect of patient gender on short-term blood pressure variability in hemodialysis patients

Increased blood pressure variability (BPV) is strongly associated with cardiovascular events in end-stage kidney disease patients. Male hemodialysis patients present higher cardiovascular risk compared with females. The aim of this study is to investigate sex differences in short-term BPV in hemodia...

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Veröffentlicht in:	Journal of human hypertension 2023-07, Vol.37 (7), p.519-523
Hauptverfasser:	Theodorakopoulou, Marieta P., Alexandrou, Maria-Eleni, Karagiannidis, Artemios G., Geladari, Virginia, Polychronidou, Georgia, Papagianni, Aikaterini, Sarafidis, Pantelis
Format:	Artikel
Sprache:	eng
Schlagworte:	692/499 692/699/1585/104 Blood Pressure Blood Pressure Monitoring, Ambulatory Cardiovascular diseases Cardiovascular Diseases - etiology Comorbidity End-stage renal disease Epidemiology Female Females Gender differences Health Administration Hemodialysis Humans Hypertension - complications Hypertension - diagnosis Hypertension - epidemiology Kidney diseases Kidney Failure, Chronic - complications Kidney Failure, Chronic - diagnosis Kidney Failure, Chronic - therapy Male Medicine Medicine & Public Health Public Health Renal Dialysis - adverse effects Sex differences Women
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Zusammenfassung:	Increased blood pressure variability (BPV) is strongly associated with cardiovascular events in end-stage kidney disease patients. Male hemodialysis patients present higher cardiovascular risk compared with females. The aim of this study is to investigate sex differences in short-term BPV in hemodialysis patients. 129 male and 91 female hemodialysis patients that underwent 48-h ABPM were included in this analysis. Standard deviation (SD), weighted SD (wSD), coefficient of variation (CV), and average real variability (ARV) of SBP and DBP were calculated with validated formulas. Age, dialysis vintage and history of major comorbidities did not differ between men and women. 48-h SBP/DBP (137.2 ± 17.4/81.9 ± 12.1 mmHg vs 132.2 ± 19.2/75.9 ± 11.7 mmHg, p = 0.045/
ISSN:	1476-5527 0950-9240 1476-5527
DOI:	10.1038/s41371-022-00725-6