Lymph node yield in the pathological staging of resected nonmetastatic colon cancer: The more the better?

Lymph node yield in the pathological staging of resected nonmetastatic colon cancer: The more the better?

IntroductionGuidelines recommend regional lymphadenectomy with a lymph node yield (LNY) of at least 12 lymph nodes (LN) for adequate colon cancer (CC) staging. LNY ≥22LN may improve survival, especially in right-sided CC [Lee et al., Surg Oncol, 27(3), 2018]. This multicentric retrospective cohort s...

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Veröffentlicht in:Surgical oncology 2022-08, Vol.43, p.101806-101806, Article 101806
Hauptverfasser: Simões, Pedro, Fernandes, Gonçalo, Costeira, Beatriz, Machete, Madalena, Baptista, Carlota, N Silva, Diana, Leal-Costa, Luísa, Prazeres, Gil, Correia, Jorge, Albuquerque, Joana, Padrão, Teresa, Gomes, Catarina, Godinho, João, Faria, Ana, Casa-Nova, Mafalda, Lopes, Fábio, Teixeira, José A, F Pulido, Catarina, Oliveira, Helena, Mascarenhas-Lemos, Luís, Albergaria, Diogo, Maio, Rui, Passos-Coelho, José L
Format: Artikel
Sprache:eng
Schlagworte:
Chemotherapy
Colon
Colon cancer
Colorectal cancer
Histology
Hospitals
Intestinal obstruction
Laparoscopy
Lymph nodes
Lymphatic system
Multivariate analysis
Patients
Surgery
Survival
Survival analysis
Tumors
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Zusammenfassung:IntroductionGuidelines recommend regional lymphadenectomy with a lymph node yield (LNY) of at least 12 lymph nodes (LN) for adequate colon cancer (CC) staging. LNY ≥22LN may improve survival, especially in right-sided CC [Lee et al., Surg Oncol, 27(3), 2018]. This multicentric retrospective cohort study evaluated the impact of LNY and tumor laterality on CC staging and survival.Materials and methodsPatients with stage I-III CC that underwent surgery from 2012 to 2018 were grouped according to LNY:
ISSN:0960-7404
1879-3320
DOI:10.1016/j.suronc.2022.101806