A novel mitochondria-targetable NIR fluorescent probe for monitoring intracellular hypobromous acid levels

A novel mitochondria-targetable NIR fluorescent probe for monitoring intracellular hypobromous acid levels

The development of ultrasensitive in situ detection techniques for monitoring hypobromous acid (HBrO) levels in the biological systems is of great significance to reveal its complex pathological and physiological effects. A simple mitochondria-targetable hydrazine-based near-infrared (NIR) fluoresce...

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Veröffentlicht in:Analytical sciences 2022-09, Vol.38 (9), p.1153-1161
Hauptverfasser: Ma, Mingshuo, Liu, Yuanyan, Chen, Jie, Yu, Shihua, Liu, Zhigang, Zeng, Xiaodan
Format: Artikel
Sprache:eng
Schlagworte:
Analytical Chemistry
Chemistry
Chemistry and Materials Science
Original Paper
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Zusammenfassung:The development of ultrasensitive in situ detection techniques for monitoring hypobromous acid (HBrO) levels in the biological systems is of great significance to reveal its complex pathological and physiological effects. A simple mitochondria-targetable hydrazine-based near-infrared (NIR) fluorescent probe ( Mito-NIR) for detecting HBrO in the mitochondria of live cells is presented in this paper. Probe Mito-NIR displays the ultrafast (
ISSN:0910-6340
1348-2246
DOI:10.1007/s44211-022-00156-w