Antibody and T-Cell Responses 6 Months After Coronavirus Disease 2019 Messenger RNA-1273 Vaccination in Patients With Chronic Kidney Disease, on Dialysis, or Living With a Kidney Transplant

Abstract Background The immune response to COVID-19 vaccination is inferior in kidney transplant recipients (KTRs) and to a lesser extent in patients on dialysis or with chronic kidney disease (CKD). We assessed the immune response 6 months after mRNA-1273 vaccination in kidney patients and compared...

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Veröffentlicht in:	Clinical infectious diseases 2023-02, Vol.76 (3), p.e188-e199
Hauptverfasser:	Sanders, Jan-Stephan F, Messchendorp, A Lianne, de Vries, Rory D, Baan, Carla C, van Baarle, Debbie, van Binnendijk, Rob, Diavatopoulos, Dimitri A, Geers, Daryl, Schmitz, Katharina S, GeurtsvanKessel, Corine H, den Hartog, Gerco, Kho, Marcia M L, Koopmans, Marion P G, van der Molen, Renate G, Remmerswaal, Ester B M, Rots, Nynke, Gansevoort, Ron T, Bemelman, Frederike J, Hilbrands, Luuk B, Reinders, Marlies E J
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibodies, Neutralizing Antibodies, Viral COVID-19 - prevention & control COVID-19 Vaccines Humans Immunoglobulin G Kidney Transplantation Renal Dialysis Renal Insufficiency, Chronic - therapy SARS-CoV-2 T-Lymphocytes Vaccination
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Zusammenfassung:	Abstract Background The immune response to COVID-19 vaccination is inferior in kidney transplant recipients (KTRs) and to a lesser extent in patients on dialysis or with chronic kidney disease (CKD). We assessed the immune response 6 months after mRNA-1273 vaccination in kidney patients and compared this to controls. Methods A total of 152 participants with CKD stages G4/5 (eGFR
ISSN:	1058-4838 1537-6591 1537-6591
DOI:	10.1093/cid/ciac557