IFNα Potentiates Immune-Checkpoint Blockade by Rewiring Metabolic Cross-talk
SUMMARYIn this issue, Hu and colleagues unveil that IFNα administration combined with anti-PD-1 therapy can potentiate murine and human CD8+ T-cell antitumor response in hepatocellular carcinoma, highlighting a novel therapeutic strategy for hepatocellular carcinoma. See related article by Hu et al....
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| Veröffentlicht in: | Cancer discovery 2022-07, Vol.12 (7), p.1615-1616 |
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| Hauptverfasser: | , , |
| Format: | Artikel |
| Sprache: | eng |
| Online-Zugang: | Volltext |
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| Zusammenfassung: | SUMMARYIn this issue, Hu and colleagues unveil that IFNα administration combined with anti-PD-1 therapy can potentiate murine and human CD8+ T-cell antitumor response in hepatocellular carcinoma, highlighting a novel therapeutic strategy for hepatocellular carcinoma. See related article by Hu et al., p. 1718 (6) . |
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| ISSN: | 2159-8274 2159-8290 |
| DOI: | 10.1158/2159-8290.CD-22-0472 |