Correlation between IgAC3 ratio and oxford score in IgA nephropathy

Background Complement activation has an important role in the pathogenesis of IgA nephropathy. Objective To determine the correlation between IgAC3 ratio (IgA/C3) and total Oxford score and predictive value of IgA/C3 in IgA nephropathy. Methods Forty-three patients diagnosed with IgA nephropathy wit...

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Veröffentlicht in:Clinical and experimental nephrology 2022-10, Vol.26 (10), p.982-987
Hauptverfasser: Karahisar Şirali, Semahat, Büberci, Refika
Format: Artikel
Sprache:eng
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Zusammenfassung:Background Complement activation has an important role in the pathogenesis of IgA nephropathy. Objective To determine the correlation between IgAC3 ratio (IgA/C3) and total Oxford score and predictive value of IgA/C3 in IgA nephropathy. Methods Forty-three patients diagnosed with IgA nephropathy with > 10 glomerular + 1 arteries in biopsy were included in the study. Hematological and biochemical variables of the blood sample taken before the biopsy and total Oxford score were recorded. The study group was divided into two groups as proteinuria ≥ 1 g (PU ≥ 1) and proteinuria 
ISSN:1342-1751
1437-7799
DOI:10.1007/s10157-022-02244-7