Bladder augmentation in exstrophy vesicae: Long‐term results of a single experienced center

Background In this study, we present our long‐term treatment outcomes of bladder augmentation (BA), bladder neck closure, and Mitrofanoff clean intermittent catheterization (CIC) in managing bladder exstrophy (BE). Methods This was a retrospective medical records' review of 33 children diagnose...

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Veröffentlicht in:Birth defects research 2022-07, Vol.114 (12), p.645-651
Hauptverfasser: Demirkan, Hasan, Kuzdan, Mehmet Özgür
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Sprache:eng
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Zusammenfassung:Background In this study, we present our long‐term treatment outcomes of bladder augmentation (BA), bladder neck closure, and Mitrofanoff clean intermittent catheterization (CIC) in managing bladder exstrophy (BE). Methods This was a retrospective medical records' review of 33 children diagnosed as born with BE, followed up at a tertiary pediatric urology clinic from 1988 to 2020. Outcomes such as surgical interventions, presence of renal calculi, hydronephrosis, and continence status were extracted. Results The median follow‐up of the group was 18.2 (4–26) years. Urinary system stones developed in 10 (30.3%) cases about 8.9 years after BA. Stone development was two times more common in patients who underwent colocystoplasty (33.3%) than those who underwent ileocytoplasty (16.6%). The state of continence of the group was satisfactory in 26 (78.7%; excellent in 23; good in 3 cases) and unsatisfactory (wet) in 6 (18.1%) cases. At the last visit, ultrasonography revealed no hydronephrosis in 23 (69.6%) patients, and the voiding cystourethrogram demonstrated low‐grade vesicoureteral reflux in 10 (30.3%) and high‐grade vesicoureteral reflux in 2 (6%) patients. Conclusions An elaborated plan of surgical reconstruction for classic BE can lead to satisfactory long‐term urinary continence in most patients. Ultimate predictors of outcome in BE repair are difficult to ascertain. Consistently, BA, bladder neck closure, and Mitrofanoff CIC continue to stand out at a critical point in the management of those patients with classic BE. Our study demonstrated that augmentation is required to achieve acceptable dryness with high satisfactory dryness rates in BE.
ISSN:2472-1727
2472-1727
DOI:10.1002/bdr2.2056