Changes in phrenic nerve compound muscle action potential in streptozotocin-induced diabetic rats

Changes in phrenic nerve compound muscle action potential in streptozotocin-induced diabetic rats

To evaluate the phrenic nerve compound muscle action potential (CMAP) in rats after diabetes mellitus (DM) induction. Twenty DM animals (intravenous streptozotocin, 45 mg.kg−1) and 25 controls underwent CMAP analysis before and 30, 60 and 90 days after DM induction. Amplitude (mV) progressively decl...

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Veröffentlicht in:Respiratory physiology & neurobiology 2022-09, Vol.303, p.103923-103923, Article 103923
Hauptverfasser: Ferrari, Marcelo C., Peixoto, João V., Fogaça, Rosalvo H., Dias, Fernando A.
Format: Artikel
Sprache:eng
Schlagworte:
Compound Muscle Action Potential
Diabetes Mellitus
Nerve Conduction
Phrenic Nerve
Rats
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Zusammenfassung:To evaluate the phrenic nerve compound muscle action potential (CMAP) in rats after diabetes mellitus (DM) induction. Twenty DM animals (intravenous streptozotocin, 45 mg.kg−1) and 25 controls underwent CMAP analysis before and 30, 60 and 90 days after DM induction. Amplitude (mV) progressively declined in DM group after 30 (Mean difference (MD): –0.915, 95 % Confidence interval (CI) –1.580 to –0.250, p 
ISSN:1569-9048
1878-1519
DOI:10.1016/j.resp.2022.103923