Learning binds new inputs into functional synaptic clusters via spinogenesis

Learning induces the formation of new excitatory synapses in the form of dendritic spines, but their functional properties remain unknown. Here, using longitudinal in vivo two-photon imaging and correlated electron microscopy of dendritic spines in the motor cortex of mice during motor learning, we...

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Veröffentlicht in:Nature neuroscience 2022-06, Vol.25 (6), p.726-737
Hauptverfasser: Hedrick, Nathan G., Lu, Zhongmin, Bushong, Eric, Singhi, Surbhi, Nguyen, Peter, Magaña, Yessenia, Jilani, Sayyed, Lim, Byung Kook, Ellisman, Mark, Komiyama, Takaki
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Sprache:eng
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