Synthesis of 3‑Allylindoles via Annulation of N‑Allyl-2-ethynylaniline Derivatives Using a P,Olefin Type Ligand/Pd(0) Catalyst

Synthesis of 3‑Allylindoles via Annulation of N‑Allyl-2-ethynylaniline Derivatives Using a P,Olefin Type Ligand/Pd(0) Catalyst

Annulation of N-allyl-2-ethynylaniline derivatives easily afforded the corresponding 2-substituted 3-allylindole derivatives in good to excellent yields using P,olefin ligand/palladium catalst systems.

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Veröffentlicht in:Journal of organic chemistry 2022-06, Vol.87 (11), p.7365-7377
Hauptverfasser: Mino, Takashi, Yamaoka, Toshiki, Watanabe, Kohei, Masuda, Chihiro, Kasano, Shohei, Yoshida, Yasushi, Takita, Ryo, Kasashima, Yoshio, Sakamoto, Masami
Format: Artikel
Sprache:eng
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Zusammenfassung:Annulation of N-allyl-2-ethynylaniline derivatives easily afforded the corresponding 2-substituted 3-allylindole derivatives in good to excellent yields using P,olefin ligand/palladium catalst systems.
ISSN:0022-3263
1520-6904
DOI:10.1021/acs.joc.2c00588